Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review

In SERS analysis, the specificity of molecular fingerprints is combined with potential single-molecule sensitivity so that is an attractive tool to detect molecules in trace amounts. Although several substrates have been widely used from early on, there are still some problems such as the difficulti...

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Main Authors: Caterina Serafinelli, Alessandro Fantoni, Elisabete C. B. A. Alegria, Manuela Vieira
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/12/4/225
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author Caterina Serafinelli
Alessandro Fantoni
Elisabete C. B. A. Alegria
Manuela Vieira
author_facet Caterina Serafinelli
Alessandro Fantoni
Elisabete C. B. A. Alegria
Manuela Vieira
author_sort Caterina Serafinelli
collection DOAJ
description In SERS analysis, the specificity of molecular fingerprints is combined with potential single-molecule sensitivity so that is an attractive tool to detect molecules in trace amounts. Although several substrates have been widely used from early on, there are still some problems such as the difficulties to bind some molecules to the substrate. With the development of nanotechnology, an increasing interest has been focused on plasmonic metal nanoparticles hybridized with (2D) nanomaterials due to their unique properties. More frequently, the excellent properties of the hybrids compounds have been used to improve the drawbacks of the SERS platforms in order to create a system with outstanding properties. In this review, the physics and working principles of SERS will be provided along with the properties of differently shaped metal nanoparticles. After that, an overview on how the hybrid compounds can be engineered to obtain the SERS platform with unique properties will be given.
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spelling doaj.art-c0e0cdf5c73f45278eb774133ae59fba2023-12-01T00:58:10ZengMDPI AGBiosensors2079-63742022-04-0112422510.3390/bios12040225Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A ReviewCaterina Serafinelli0Alessandro Fantoni1Elisabete C. B. A. Alegria2Manuela Vieira3Instituto Superior de Engenharia de Lisboa—Instituto Politécnico de Lisboa, 1949-014 Lisboa, PortugalInstituto Superior de Engenharia de Lisboa—Instituto Politécnico de Lisboa, 1949-014 Lisboa, PortugalInstituto Superior de Engenharia de Lisboa—Instituto Politécnico de Lisboa, 1949-014 Lisboa, PortugalInstituto Superior de Engenharia de Lisboa—Instituto Politécnico de Lisboa, 1949-014 Lisboa, PortugalIn SERS analysis, the specificity of molecular fingerprints is combined with potential single-molecule sensitivity so that is an attractive tool to detect molecules in trace amounts. Although several substrates have been widely used from early on, there are still some problems such as the difficulties to bind some molecules to the substrate. With the development of nanotechnology, an increasing interest has been focused on plasmonic metal nanoparticles hybridized with (2D) nanomaterials due to their unique properties. More frequently, the excellent properties of the hybrids compounds have been used to improve the drawbacks of the SERS platforms in order to create a system with outstanding properties. In this review, the physics and working principles of SERS will be provided along with the properties of differently shaped metal nanoparticles. After that, an overview on how the hybrid compounds can be engineered to obtain the SERS platform with unique properties will be given.https://www.mdpi.com/2079-6374/12/4/225SERS analysisplasmonic metal nanoparticleshotspotshybrid materials
spellingShingle Caterina Serafinelli
Alessandro Fantoni
Elisabete C. B. A. Alegria
Manuela Vieira
Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review
Biosensors
SERS analysis
plasmonic metal nanoparticles
hotspots
hybrid materials
title Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review
title_full Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review
title_fullStr Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review
title_full_unstemmed Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review
title_short Plasmonic Metal Nanoparticles Hybridized with 2D Nanomaterials for SERS Detection: A Review
title_sort plasmonic metal nanoparticles hybridized with 2d nanomaterials for sers detection a review
topic SERS analysis
plasmonic metal nanoparticles
hotspots
hybrid materials
url https://www.mdpi.com/2079-6374/12/4/225
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AT alessandrofantoni plasmonicmetalnanoparticleshybridizedwith2dnanomaterialsforsersdetectionareview
AT elisabetecbaalegria plasmonicmetalnanoparticleshybridizedwith2dnanomaterialsforsersdetectionareview
AT manuelavieira plasmonicmetalnanoparticleshybridizedwith2dnanomaterialsforsersdetectionareview