Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic review
ObjectiveWe performed this systemic review to investigate the therapeutic potential and safety of adjunctive accelerated repetitive transcranial magnetic stimulation (aTMS) for older patients with depression.MethodsWe included published randomized clinical trials (RCTs) and observational studies tar...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1036676/full |
| _version_ | 1811235554072723456 |
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| author | Wei Zheng Xin-Yang Zhang Rui Xu Xiong Huang Ying-Jun Zheng Xing-Bing Huang Ze-Zhi Li Huo-Di Chen |
| author_facet | Wei Zheng Xin-Yang Zhang Rui Xu Xiong Huang Ying-Jun Zheng Xing-Bing Huang Ze-Zhi Li Huo-Di Chen |
| author_sort | Wei Zheng |
| collection | DOAJ |
| description | ObjectiveWe performed this systemic review to investigate the therapeutic potential and safety of adjunctive accelerated repetitive transcranial magnetic stimulation (aTMS) for older patients with depression.MethodsWe included published randomized clinical trials (RCTs) and observational studies targeting adjunctive aTMS for older patients with depression.ResultsTwo open-label self-controlled studies (n = 29) fulfilled the criteria for inclusion. The included studies reported significant improvements in depressive symptoms from baseline to post-aTMS (all Ps < 0.05). One study reported a dropout rate of 10.5% (2/19). Mild headache was the most common adverse reaction.ConclusionThe currently available evidence from two open-label self-controlled studies indicates that adjunctive aTMS is a safe and effective therapy for older patients with depression. |
| first_indexed | 2024-04-12T11:54:08Z |
| format | Article |
| id | doaj.art-c0e64021c9e34ba29b6bf7926549bc74 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-12T11:54:08Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-c0e64021c9e34ba29b6bf7926549bc742022-12-22T03:34:06ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652022-10-011410.3389/fnagi.2022.10366761036676Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic reviewWei Zheng0Xin-Yang Zhang1Rui Xu2Xiong Huang3Ying-Jun Zheng4Xing-Bing Huang5Ze-Zhi Li6Huo-Di Chen7The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaLaboratory of Laser Sports Medicine, School of Sports Science, South China Normal University, Guangzhou, ChinaObjectiveWe performed this systemic review to investigate the therapeutic potential and safety of adjunctive accelerated repetitive transcranial magnetic stimulation (aTMS) for older patients with depression.MethodsWe included published randomized clinical trials (RCTs) and observational studies targeting adjunctive aTMS for older patients with depression.ResultsTwo open-label self-controlled studies (n = 29) fulfilled the criteria for inclusion. The included studies reported significant improvements in depressive symptoms from baseline to post-aTMS (all Ps < 0.05). One study reported a dropout rate of 10.5% (2/19). Mild headache was the most common adverse reaction.ConclusionThe currently available evidence from two open-label self-controlled studies indicates that adjunctive aTMS is a safe and effective therapy for older patients with depression.https://www.frontiersin.org/articles/10.3389/fnagi.2022.1036676/fullaccelerated TMSdepressionsystematic reviewolder patientsresponse |
| spellingShingle | Wei Zheng Xin-Yang Zhang Rui Xu Xiong Huang Ying-Jun Zheng Xing-Bing Huang Ze-Zhi Li Huo-Di Chen Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic review Frontiers in Aging Neuroscience accelerated TMS depression systematic review older patients response |
| title | Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic review |
| title_full | Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic review |
| title_fullStr | Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic review |
| title_full_unstemmed | Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic review |
| title_short | Adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression: A systematic review |
| title_sort | adjunctive accelerated repetitive transcranial magnetic stimulation for older patients with depression a systematic review |
| topic | accelerated TMS depression systematic review older patients response |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2022.1036676/full |
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