Aberrant Methylation of LINE-1 Transposable Elements: A Search for Cancer Biomarkers
Cancer remains one of the main causes of human mortality despite significant progress in its diagnostics and therapy achieved in the past decade. Massive hypomethylation of retrotransposons, in particular LINE-1, is considered a hallmark of most malignant transformations as it results in the reactiv...
Main Authors: | Anastasia A. Ponomaryova, Elena Y. Rykova, Polina A. Gervas, Nadezhda V. Cherdyntseva, Ilgar Z. Mamedov, Tatyana L. Azhikina |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/9/2017 |
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