High resolution respirometry to assess function of mitochondria in native homogenates of human heart muscle.
Impaired myocardial bioenergetics is a hallmark of many cardiac diseases. There is a need of a simple and reproducible method of assessment of mitochondrial function from small human myocardial tissue samples. In this study we adopted high-resolution respirometry to homogenates of fresh human cardia...
Main Authors: | Adéla Krajčová, Tomáš Urban, David Megvinet, Petr Waldauf, Martin Balík, Jan Hlavička, Petr Budera, Libor Janoušek, Eva Pokorná, František Duška |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0226142 |
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