Lack of Vesicular Zinc Does Not Affect the Behavioral Phenotype of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation Mice

Lack of Vesicular Zinc Does Not Affect the Behavioral Phenotype of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation Mice

Zinc is important in neural and synaptic development and neuronal transmission. Within the brain, zinc transporter 3 (ZnT3) is essential for zinc uptake into vesicles. Loss of vesicular zinc has been shown to produce neurodevelopmental disorder (NDD)-like behavior, such as decreased social interacti...

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Bibliographic Details
Main Authors: Katy Celina Sandoval, Sarah E. Thackray, Alison Wong, Nicole Niewinski, Colten Chipak, Suhkjinder Rehal, Richard H. Dyck
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
vesicular zinc
maternal immune activation
autism spectrum disorders
schizophrenia
polyI:C
behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.769322/full

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