Immunofluorescence signal intensity measurements as a semi-quantitative tool to assess sarcoglycan complex expression in muscle biopsy

Immunofluorescence signal intensity measurements as a semi-quantitative tool to assess sarcoglycan complex expression in muscle biopsy

Sarcoglycanopathies are highly heterogeneous in terms of disease progression, muscular weakness, loss of ambulation and cardiac/respiratory involvement. Their clinical severity usually correlates with the residual protein amount, which makes protein quantification extremely relevant. Sarcoglycanopa...

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Bibliographic Details
Main Authors: Simona Zanotti, Francesca Magri, Francesca Poggetti, Michela Ripolone, Daniele Velardo, Francesco Fortunato, Patrizia Ciscato, Maurizio Moggio, Stefania Corti, Giacomo Pietro Comi, Monica Sciacco
Format: Article
Language:English
Published: PAGEPress Publications 2022-09-01
Series:European Journal of Histochemistry
Subjects:
sarcoglycans
immunofluorescence
protein quantification
histology
fibrosis
Online Access:https://www.ejh.it/index.php/ejh/article/view/3418

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