A simplified workflow with end-point validation of real-time electrical cell-substrate impedance sensing of retinoic acid stimulated neurogenesis in human SH-SY5Y cells in vitro

A simplified workflow with end-point validation of real-time electrical cell-substrate impedance sensing of retinoic acid stimulated neurogenesis in human SH-SY5Y cells in vitro

Abstract Objective Retinoic acid (RA) is known to transition proliferating SH-SY5Y neuroblastoma cells towards functional neurons. However, the activity of RA is restricted due to its photolability where any findings from prolonged time course observations using microscopy may alter outcomes. The ai...

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Bibliographic Details
Main Authors: Julia Joos-Vandewalle, Vanessa Steenkamp, Earl Prinsloo
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Research Notes
Subjects:
Electric cell-substrate impedance sensor
Neurogenesis
Differentiation
Neurite outgrowth
SH-SY5Y neuroblastoma
Online Access:https://doi.org/10.1186/s13104-023-06369-0

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