Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two
Purpose: To evaluate of retinal morphology and function progress in patients with diabetes type 2 and DME consistent with the level of pathogenetic factor in tear fluid.Methods: The progress of visual acuity, retinal thickness and photosensitivity after ranibizumab intravitreal injection has been as...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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Ophthalmology Publishing Group
2014-07-01
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| Series: | Oftalʹmologiâ |
| Subjects: | |
| Online Access: | https://www.ophthalmojournal.com/opht/article/view/54 |
| _version_ | 1827063288599412736 |
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| author | L. K. Moshetova I. V. Vorobieva E. V. Parfenova D. A. Merkushenkova P. I. Makarevich V. I. Alekhnovich |
| author_facet | L. K. Moshetova I. V. Vorobieva E. V. Parfenova D. A. Merkushenkova P. I. Makarevich V. I. Alekhnovich |
| author_sort | L. K. Moshetova |
| collection | DOAJ |
| description | Purpose: To evaluate of retinal morphology and function progress in patients with diabetes type 2 and DME consistent with the level of pathogenetic factor in tear fluid.Methods: The progress of visual acuity, retinal thickness and photosensitivity after ranibizumab intravitreal injection has been assessed.Results: Statistically significant increase in visual acuity, retinal photosensitivity, decrease of retinal thickness and VEGF A level was found in the tear fluid after injection. The correlation of VEGF level in tear fluid with visual acuity after procedure was found to be negative. Conclusion: Ranibizumab intravitreal injection is a pathogenic treatment leading to morphological and functional retinal state improvement. |
| first_indexed | 2024-04-10T01:49:13Z |
| format | Article |
| id | doaj.art-c0ed0611f0dd4500a9d5b2e31b39f5ff |
| institution | Directory Open Access Journal |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| last_indexed | 2025-02-18T20:11:08Z |
| publishDate | 2014-07-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj.art-c0ed0611f0dd4500a9d5b2e31b39f5ff2024-10-17T16:11:54ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-01101505510.18008/1816-5095-2013-1-50-5554Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type twoL. K. Moshetova0I. V. Vorobieva1E. V. Parfenova2D. A. Merkushenkova3P. I. Makarevich4V. I. Alekhnovich5ГБОУ ДПО РМАПО Министерства здравоохранения РоссииГБОУ ДПО РМАПО Министерства здравоохранения РоссииФГБОУ ВПО МГУ им. М. В. ЛомоносоваГБОУ ДПО РМАПО Министерства здравоохранения РоссииФГБОУ ВПО МГУ им. М. В. ЛомоносоваФГБОУ ВПО МГТУ им. Н. Э. БауманаPurpose: To evaluate of retinal morphology and function progress in patients with diabetes type 2 and DME consistent with the level of pathogenetic factor in tear fluid.Methods: The progress of visual acuity, retinal thickness and photosensitivity after ranibizumab intravitreal injection has been assessed.Results: Statistically significant increase in visual acuity, retinal photosensitivity, decrease of retinal thickness and VEGF A level was found in the tear fluid after injection. The correlation of VEGF level in tear fluid with visual acuity after procedure was found to be negative. Conclusion: Ranibizumab intravitreal injection is a pathogenic treatment leading to morphological and functional retinal state improvement.https://www.ophthalmojournal.com/opht/article/view/54diabetic macular edemaangiogenesis inhibitorvegf |
| spellingShingle | L. K. Moshetova I. V. Vorobieva E. V. Parfenova D. A. Merkushenkova P. I. Makarevich V. I. Alekhnovich Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two Oftalʹmologiâ diabetic macular edema angiogenesis inhibitor vegf |
| title | Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two |
| title_full | Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two |
| title_fullStr | Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two |
| title_full_unstemmed | Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two |
| title_short | Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two |
| title_sort | сlinical functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two |
| topic | diabetic macular edema angiogenesis inhibitor vegf |
| url | https://www.ophthalmojournal.com/opht/article/view/54 |
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