Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls

Background: Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions. Aim: Our aim was to demonstrate the effective...

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Main Authors: Sunita Singh, Natasha Garg, Sumiti Gupta, Nisha Marwah, Rajneesh Kalra, Virender Singh, Rajeev Sen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Journal of Cytology
Subjects:
Online Access:http://www.jcytol.org/article.asp?issn=0970-9371;year=2011;volume=28;issue=3;spage=93;epage=97;aulast=Singh
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author Sunita Singh
Natasha Garg
Sumiti Gupta
Nisha Marwah
Rajneesh Kalra
Virender Singh
Rajeev Sen
author_facet Sunita Singh
Natasha Garg
Sumiti Gupta
Nisha Marwah
Rajneesh Kalra
Virender Singh
Rajeev Sen
author_sort Sunita Singh
collection DOAJ
description Background: Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions. Aim: Our aim was to demonstrate the effectiveness of this cheap and simple procedure for the diagnosis of tumor and tumor like lesions of oral and maxillofacial region. In addition, we sought to highlight probable causes of errors in the cases showing lack of correlation between cytological and histological diagnoses. Materials and Methods: The study was conducted on 50 patients of all age groups with various palpable lesions in the oromaxillofacial region. A comparison between cytological and histological diagnosis was done wherever biopsy material was available. Results: The rate of unsatisfactory FNA was 4%. There were six false negative cases but no false positive case. The sensitivity of our study ranged from 77.7 to 75% including and excluding the suspicious cases, respectively. Specificity and positive predictive value was 100%. Conclusion: FNAC is a minimally invasive, highly accurate and cost-effective procedure for the assessment of patients with oromaxillofacial lesions. When applied in a proper manner, FNAC can help avoid a surgical biopsy in many cases.
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spelling doaj.art-c0ed6aade6d14bffac3374d38d64403b2022-12-22T00:57:28ZengWolters Kluwer Medknow PublicationsJournal of Cytology0970-93712011-01-01283939710.4103/0970-9371.83461Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfallsSunita SinghNatasha GargSumiti GuptaNisha MarwahRajneesh KalraVirender SinghRajeev SenBackground: Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions. Aim: Our aim was to demonstrate the effectiveness of this cheap and simple procedure for the diagnosis of tumor and tumor like lesions of oral and maxillofacial region. In addition, we sought to highlight probable causes of errors in the cases showing lack of correlation between cytological and histological diagnoses. Materials and Methods: The study was conducted on 50 patients of all age groups with various palpable lesions in the oromaxillofacial region. A comparison between cytological and histological diagnosis was done wherever biopsy material was available. Results: The rate of unsatisfactory FNA was 4%. There were six false negative cases but no false positive case. The sensitivity of our study ranged from 77.7 to 75% including and excluding the suspicious cases, respectively. Specificity and positive predictive value was 100%. Conclusion: FNAC is a minimally invasive, highly accurate and cost-effective procedure for the assessment of patients with oromaxillofacial lesions. When applied in a proper manner, FNAC can help avoid a surgical biopsy in many cases.http://www.jcytol.org/article.asp?issn=0970-9371;year=2011;volume=28;issue=3;spage=93;epage=97;aulast=SinghFine needle aspiration cytology; oral and maxillofacial lesions; pitfalls
spellingShingle Sunita Singh
Natasha Garg
Sumiti Gupta
Nisha Marwah
Rajneesh Kalra
Virender Singh
Rajeev Sen
Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls
Journal of Cytology
Fine needle aspiration cytology; oral and maxillofacial lesions; pitfalls
title Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls
title_full Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls
title_fullStr Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls
title_full_unstemmed Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls
title_short Fine needle aspiration cytology in lesions of oral and maxillofacial region: Diagnostic pitfalls
title_sort fine needle aspiration cytology in lesions of oral and maxillofacial region diagnostic pitfalls
topic Fine needle aspiration cytology; oral and maxillofacial lesions; pitfalls
url http://www.jcytol.org/article.asp?issn=0970-9371;year=2011;volume=28;issue=3;spage=93;epage=97;aulast=Singh
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