S100B Up-Regulates Macrophage Production of IL1β and CCL22 and Influences Severity of Retinal Inflammation.

S100B is a Ca2+ binding protein and is typically associated with brain and CNS disorders. However, the role of S100B in an inflammatory situation is not clear. The aim of the study was to determine whether S100B is likely to influence inflammation through its effect on macrophages. A murine macropha...

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Bibliographic Details
Main Authors: Jennifer Niven, Joseph Hoare, Debbie McGowan, Gayathri Devarajan, Shigeyoshi Itohara, Monique Gannagé, Peter Teismann, Isabel Crane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4512682?pdf=render