The future of immunopsychiatry: Three milestones to clinical innovation

Psychoneuroimmunology, the area of research dedicated to understanding the fundamental interactions between the central nervous system and the immune system, has given rise to the development of Immunopsychiatry, a new discipline which harnesses the immune system to produce beneficial outcomes for m...

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Main Author: L.J. De Picker, MD PhD
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354621001174
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author L.J. De Picker, MD PhD
author_facet L.J. De Picker, MD PhD
author_sort L.J. De Picker, MD PhD
collection DOAJ
description Psychoneuroimmunology, the area of research dedicated to understanding the fundamental interactions between the central nervous system and the immune system, has given rise to the development of Immunopsychiatry, a new discipline which harnesses the immune system to produce beneficial outcomes for mental health problems. Immunopsychiatry has the potential to become a clinically relevant specialty area in psychiatric practice, but has not yet been adopted by the wider mental health community. This paper aims to map out the future trajectory of Immunopsychiatry on its road towards science-to-policy knowledge translation and clinical implementation. Three critical milestones which will need to be reached in order for Immunopsychiatry to fulfil its promise for clinical innovation are discussed: a clear definition of patients who fall within the immunopsychiatric continuum; demonstration of well-defined clinical benefit and incorporation in clinical guidelines; and convergence with other paradigms in biological psychiatry.
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spelling doaj.art-c0eea101f00b41ccabdd75fe922042792022-12-21T23:30:12ZengElsevierBrain, Behavior, & Immunity - Health2666-35462021-10-0116100314The future of immunopsychiatry: Three milestones to clinical innovationL.J. De Picker, MD PhD0University Psychiatric Hospital Campus Duffel, Duffel, Belgium; Collaborative Antwerp Psychiatric Research Institute, University of Antwerp, Antwerp, Belgium; University Psychiatric Hospital Campus Duffel, Duffel, Belgium.Psychoneuroimmunology, the area of research dedicated to understanding the fundamental interactions between the central nervous system and the immune system, has given rise to the development of Immunopsychiatry, a new discipline which harnesses the immune system to produce beneficial outcomes for mental health problems. Immunopsychiatry has the potential to become a clinically relevant specialty area in psychiatric practice, but has not yet been adopted by the wider mental health community. This paper aims to map out the future trajectory of Immunopsychiatry on its road towards science-to-policy knowledge translation and clinical implementation. Three critical milestones which will need to be reached in order for Immunopsychiatry to fulfil its promise for clinical innovation are discussed: a clear definition of patients who fall within the immunopsychiatric continuum; demonstration of well-defined clinical benefit and incorporation in clinical guidelines; and convergence with other paradigms in biological psychiatry.http://www.sciencedirect.com/science/article/pii/S2666354621001174ImmunopsychiatryPsychoneuroimmunologyTranslationalPolicyPsychiatryInnovation
spellingShingle L.J. De Picker, MD PhD
The future of immunopsychiatry: Three milestones to clinical innovation
Brain, Behavior, & Immunity - Health
Immunopsychiatry
Psychoneuroimmunology
Translational
Policy
Psychiatry
Innovation
title The future of immunopsychiatry: Three milestones to clinical innovation
title_full The future of immunopsychiatry: Three milestones to clinical innovation
title_fullStr The future of immunopsychiatry: Three milestones to clinical innovation
title_full_unstemmed The future of immunopsychiatry: Three milestones to clinical innovation
title_short The future of immunopsychiatry: Three milestones to clinical innovation
title_sort future of immunopsychiatry three milestones to clinical innovation
topic Immunopsychiatry
Psychoneuroimmunology
Translational
Policy
Psychiatry
Innovation
url http://www.sciencedirect.com/science/article/pii/S2666354621001174
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