Predicting the apolipoprotein E ε4 allele carrier status based on gray matter volumes and cognitive function

Predicting the apolipoprotein E ε4 allele carrier status based on gray matter volumes and cognitive function

Abstract Background Apolipoprotein E (ApoE) ε4 carriers have a higher risk of developing Alzheimer's disease (AD) and show brain atrophy and cognitive decline even before diagnosis. Objective To predict ApoE ε4 status using gray matter volume (GMV) obtained from magnetic resonance imaging image...

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Bibliographic Details
Main Authors: Hyug‐Gi Kim, Yunan Tian, Sue Min Jung, Soonchan Park, Hak Young Rhee, Chang‐Woo Ryu, Geon‐Ho Jahng
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Brain and Behavior
Subjects:
aging
apolipoprotein E ε4 status
brain atrophy
cognitive decline
machine learning
prediction
Online Access:https://doi.org/10.1002/brb3.3381

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