Updated definition of exercise pulmonary hypertension

In the recently published European Society of Cardiology/European Respiratory Society guidelines on the diagnosis and treatment of pulmonary hypertension (PH) the haemodynamic definitions of PH were updated and a new definition for exercise PH was introduced. Accordingly, exercise PH is characterise...

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Main Authors: Katarina Zeder, Horst Olschewski, Gabor Kovacs
Format: Article
Language:English
Published: European Respiratory Society 2022-12-01
Series:Breathe
Online Access:http://breathe.ersjournals.com/content/18/4/220232.full
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author Katarina Zeder
Horst Olschewski
Gabor Kovacs
author_facet Katarina Zeder
Horst Olschewski
Gabor Kovacs
author_sort Katarina Zeder
collection DOAJ
description In the recently published European Society of Cardiology/European Respiratory Society guidelines on the diagnosis and treatment of pulmonary hypertension (PH) the haemodynamic definitions of PH were updated and a new definition for exercise PH was introduced. Accordingly, exercise PH is characterised by a mean pulmonary arterial pressure/cardiac output (CO) slope >3 Wood units (WU) from rest to exercise. This threshold is supported by several studies demonstrating prognostic and diagnostic relevance of exercise haemodynamics in various patient cohorts. From a differential diagnostic point of view, an elevated pulmonary arterial wedge pressure/CO slope >2 WU may be suitable to identify post-capillary causes of exercise PH. Right heart catheterisation remains the gold standard to assess pulmonary haemodynamics both at rest and exercise. In this review, we discuss the evidence that led to the reintroduction of exercise PH in the PH definitions.
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spelling doaj.art-c0f431c4e0e94aea93248c98fe5b78212023-03-01T07:06:39ZengEuropean Respiratory SocietyBreathe1810-68382073-47352022-12-0118410.1183/20734735.0232-20220232-2022Updated definition of exercise pulmonary hypertensionKatarina Zeder0Horst Olschewski1Gabor Kovacs2 Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria In the recently published European Society of Cardiology/European Respiratory Society guidelines on the diagnosis and treatment of pulmonary hypertension (PH) the haemodynamic definitions of PH were updated and a new definition for exercise PH was introduced. Accordingly, exercise PH is characterised by a mean pulmonary arterial pressure/cardiac output (CO) slope >3 Wood units (WU) from rest to exercise. This threshold is supported by several studies demonstrating prognostic and diagnostic relevance of exercise haemodynamics in various patient cohorts. From a differential diagnostic point of view, an elevated pulmonary arterial wedge pressure/CO slope >2 WU may be suitable to identify post-capillary causes of exercise PH. Right heart catheterisation remains the gold standard to assess pulmonary haemodynamics both at rest and exercise. In this review, we discuss the evidence that led to the reintroduction of exercise PH in the PH definitions.http://breathe.ersjournals.com/content/18/4/220232.full
spellingShingle Katarina Zeder
Horst Olschewski
Gabor Kovacs
Updated definition of exercise pulmonary hypertension
Breathe
title Updated definition of exercise pulmonary hypertension
title_full Updated definition of exercise pulmonary hypertension
title_fullStr Updated definition of exercise pulmonary hypertension
title_full_unstemmed Updated definition of exercise pulmonary hypertension
title_short Updated definition of exercise pulmonary hypertension
title_sort updated definition of exercise pulmonary hypertension
url http://breathe.ersjournals.com/content/18/4/220232.full
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