Efficacy of recombinant Bacillus Calmette-Guérin containing dltA in in vivo three-dimensional bio-printed bladder cancer-on-a-chip and ex vivo orthotopic mouse model

Efficacy of recombinant Bacillus Calmette-Guérin containing dltA in in vivo three-dimensional bio-printed bladder cancer-on-a-chip and ex vivo orthotopic mouse model

Purpose: We investigated the efficacy and optimal dosage of recombinant Bacillus Calmette-Guérin-dltA (rBCG-dltA) in a high-throughput 3D bio-printed bladder cancer-on-a-chip (BCOC) and orthotopic bladder cancer mouse model. Materials and Methods: We fabricated high-throughput BCOC with microfluidi...

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Bibliographic Details
Main Authors: Joongwon Choi, Tae Young Jung, Jung Hoon Kim, Sejung Maeng, Su Jeong Kang, Mirinae Kim, Young Wook Choi, Se Young Choi, Sung-Hwan Kim, In Ho Chang
Format: Article
Language:English
Published: Korean Urological Association 2023-05-01
Series:Investigative and Clinical Urology
Subjects:
bioprinting
mycobacterium bovis
tumor microenvironment
Online Access:https://www.icurology.org/pdf/10.4111/icu.20220293

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