Comprehensive chromosomal aberrations in a case of a patient with TCF3-HLF-positive BCP-ALL

Comprehensive chromosomal aberrations in a case of a patient with TCF3-HLF-positive BCP-ALL

Abstract Background The use of high-throughput analytical techniques has enabled the description of acute lymphoblastic leukaemia (ALL) subtypes. The TCF3-HLF translocation is a very rare rearrangement in ALL that is associated with an extremely poor prognosis. The TCF3-HLF fusion gene in the descri...

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Bibliographic Details
Main Authors: Monika Lejman, Monika Włodarczyk, Joanna Zawitkowska, Jerzy R. Kowalczyk
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Medical Genomics
Subjects:
Acute lymphoblastic leukaemia
Case report
TCF3-HLF
Molecular abnormalities
Gene fusion
RB1
Online Access:http://link.springer.com/article/10.1186/s12920-020-0709-y

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