The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family
The mating-type switching endonuclease HO plays a central role in the natural life cycle of Saccharomyces cerevisiae, but its evolutionary origin is unknown. HO is a recent addition to yeast genomes, present in only a few genera close to Saccharomyces. Here we show that HO is structurally and phylog...
Main Authors: | Aisling Y Coughlan, Lisa Lombardi, Stephanie Braun-Galleani, Alexandre AR Martos, Virginie Galeote, Frédéric Bigey, Sylvie Dequin, Kevin P Byrne, Kenneth H Wolfe |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/55336 |
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