Repurposing FDA-approved drugs as therapeutics to treat Rift Valley fever virus infection

Repurposing FDA-approved drugs as therapeutics to treat Rift Valley fever virus infection

There are currently no FDA-approved therapeutics available to treat Rift Valley fever virus (RVFV) infection. In an effort to repurpose drugs for RVFV treatment, a library of FDA-approved drugs was screened to determine their ability to inhibit RVFV. Several drugs from varying compound classes, inc...

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Bibliographic Details
Main Authors: Ashwini eBenedict, Neha eBansal, Svetlana eSenina, Idris eHooper, Lindsay eLundberg, Cynthia ede la Fuente, Aarthi eNarayanan, Bradford eGutting, Kylene eKehn-Hall
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Microbiology
Subjects:
Rift Valley fever virus
replication
fda
Sorafenib
viral egress
Raf
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00676/full

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