Decoding the centromeric nucleosome through CENP-N

Decoding the centromeric nucleosome through CENP-N

Centromere protein (CENP) A, a histone H3 variant, is a key epigenetic determinant of chromosome domains known as centromeres. Centromeres nucleate kinetochores, multi-subunit complexes that capture spindle microtubules to promote chromosome segregation during mitosis. Two kinetochore proteins, CENP...

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Bibliographic Details
Main Authors: Satyakrishna Pentakota, Keda Zhou, Charlotte Smith, Stefano Maffini, Arsen Petrovic, Garry P Morgan, John R Weir, Ingrid R Vetter, Andrea Musacchio, Karolin Luger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
centromere
kinetochore
CENP-A
CENP-N
CENP-C
mitosis
Online Access:https://elifesciences.org/articles/33442

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