Upregulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of herpes simplex virus type 1

Upregulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of herpes simplex virus type 1

Abstract Background Nuclear factor E2-related factor 2 (Nrf2) is an important transcription factor which plays a pivotal role in detoxifying reactive oxygen species (ROS) and has been more recently shown to regulate inflammatory and antiviral responses. However, the role of Nrf2 in Herpes Simplex Vi...

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Bibliographic Details
Main Authors: Li Zhang, Jiao Wang, Zhan Wang, Ying Li, Hui Wang, Hongtu Liu
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Virology Journal
Subjects:
Nuclear factor E2-related factor 2 (Nrf2)
Herpes simplex virus type 1 (HSV-1)
Oxidative stress
Heme oxygenase-1 (HO-1)
NAD(P)H quinone oxidoreductase 1 (NQO1)
Online Access:https://doi.org/10.1186/s12985-021-01733-7

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