Coumarin Derivatives Inhibit ADP-Induced Platelet Activation and Aggregation

Coumarin Derivatives Inhibit ADP-Induced Platelet Activation and Aggregation

Coumarin was first discovered in Tonka bean and then widely in other plants. Coumarin has an anticoagulant effect, and its derivative, warfarin, is a vitamin K analogue that inhibits the synthesis of clotting factors and is more widely used in the clinical treatment of endovascular embolism. At pres...

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Bibliographic Details
Main Authors: Ping-Hsun Lu, Tzu-Hsien Liao, Yau-Hung Chen, Yeng-Ling Hsu, Chan-Yen Kuo, Chuan-Chi Chan, Lu-Kai Wang, Ching-Yuh Chern, Fu-Ming Tsai
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
coumarin
platelets
ADP
aggregation
7-hydroxyflavone
flavonoids
Online Access:https://www.mdpi.com/1420-3049/27/13/4054

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