The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smears

"nBackground: The papanicolaou (pap) smear has been used to screen cervical cancer since 1940. Recently, a number of new technologies have been developed to improve the detection of cervical cancer and its precursors. However, there is substantial controversy about whether the new tests off...

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Main Authors: Izadi Mood N, Dehdashti MR, Eftekhar Z, Ahmadi SA
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2009-03-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/12808.pdf&manuscript_id=12808
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author Izadi Mood N
Dehdashti MR
Eftekhar Z
Ahmadi SA
author_facet Izadi Mood N
Dehdashti MR
Eftekhar Z
Ahmadi SA
author_sort Izadi Mood N
collection DOAJ
description "nBackground: The papanicolaou (pap) smear has been used to screen cervical cancer since 1940. Recently, a number of new technologies have been developed to improve the detection of cervical cancer and its precursors. However, there is substantial controversy about whether the new tests offer meaningful advantages over the conventional pap smear. Ideally, these new tests will increase the early detection of meaningful pap smear abnormalities, reduce the number of unsatisfactory smears and provide fewer ambiguous results. "nMethods: In this prospective study the result of Liquid- based cytology smears (Liquid prep method) compared with conventional pap smears in terms of adequacy and ASC diagnosis in 289 patients in pathology department of mirza kochak khan hospital (Tehran, 2005- 2006). The smears were interpreted based on Bethesda system 2001. "nResults: In conventional pap smear method, the number of occasions of unsatisfactory smear was 24(5%). In Liquid- based cytology method 66(22.8%) smears were unsatisfactory, In which difference between unsatisfactory groups were statistically significant (p<0.05), Also ASC diagnosis in conventional method 5(1.8%) as compared with Liquid- based cytology 6(2.1%), was not statistically significant (p>0.05). "nConclusions: There was no significant difference between two methods in term of ASC diagnosis but in conventional method adequacy of specimen was significantly better as compared with this Liquid- based cytology method.
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spelling doaj.art-c10467d67bec4184897d2298366915d62022-12-22T01:35:19ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222009-03-016612900906The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smearsIzadi Mood NDehdashti MREftekhar ZAhmadi SA"nBackground: The papanicolaou (pap) smear has been used to screen cervical cancer since 1940. Recently, a number of new technologies have been developed to improve the detection of cervical cancer and its precursors. However, there is substantial controversy about whether the new tests offer meaningful advantages over the conventional pap smear. Ideally, these new tests will increase the early detection of meaningful pap smear abnormalities, reduce the number of unsatisfactory smears and provide fewer ambiguous results. "nMethods: In this prospective study the result of Liquid- based cytology smears (Liquid prep method) compared with conventional pap smears in terms of adequacy and ASC diagnosis in 289 patients in pathology department of mirza kochak khan hospital (Tehran, 2005- 2006). The smears were interpreted based on Bethesda system 2001. "nResults: In conventional pap smear method, the number of occasions of unsatisfactory smear was 24(5%). In Liquid- based cytology method 66(22.8%) smears were unsatisfactory, In which difference between unsatisfactory groups were statistically significant (p<0.05), Also ASC diagnosis in conventional method 5(1.8%) as compared with Liquid- based cytology 6(2.1%), was not statistically significant (p>0.05). "nConclusions: There was no significant difference between two methods in term of ASC diagnosis but in conventional method adequacy of specimen was significantly better as compared with this Liquid- based cytology method.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/12808.pdf&manuscript_id=12808Conventional pap smearliquid based cytologyspecimen adequacyASC
spellingShingle Izadi Mood N
Dehdashti MR
Eftekhar Z
Ahmadi SA
The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smears
Tehran University Medical Journal
Conventional pap smear
liquid based cytology
specimen adequacy
ASC
title The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smears
title_full The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smears
title_fullStr The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smears
title_full_unstemmed The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smears
title_short The specimen adequacy and Atypical Squamous Cell frequency: conventional versus liquid-based cytology pap smears
title_sort specimen adequacy and atypical squamous cell frequency conventional versus liquid based cytology pap smears
topic Conventional pap smear
liquid based cytology
specimen adequacy
ASC
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/12808.pdf&manuscript_id=12808
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