Size matters: how sample size affects the reproducibility and specificity of gene set analysis

Size matters: how sample size affects the reproducibility and specificity of gene set analysis

Abstract Background Gene set analysis is a well-established approach for interpretation of data from high-throughput gene expression studies. Achieving reproducible results is an essential requirement in such studies. One factor of a gene expression experiment that can affect reproducibility is the...

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Bibliographic Details
Main Authors: Farhad Maleki, Katie Ovens, Ian McQuillan, Anthony J. Kusalik
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Human Genomics
Subjects:
Gene expression
Gene set analysis
Enrichment analysis
Sample size
Specificity
Online Access:http://link.springer.com/article/10.1186/s40246-019-0226-2

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