Pressure Overload Greatly Promotes Neonatal Right Ventricular Cardiomyocyte Proliferation: A New Model for the Study of Heart Regeneration

Pressure Overload Greatly Promotes Neonatal Right Ventricular Cardiomyocyte Proliferation: A New Model for the Study of Heart Regeneration

Background Current mammalian models for heart regeneration research are limited to neonatal apex amputation and myocardial infarction, both of which are controversial. RNAseq has demonstrated a very limited set of differentially expressed genes between sham and operated hearts in myocardial infarcti...

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Bibliographic Details
Main Authors: Lincai Ye, Shoubao Wang, Yingying Xiao, Chuan Jiang, Yanhui Huang, Huiwen Chen, Haibo Zhang, Hao Zhang, Jinfen Liu, Zhuoming Xu, Haifa Hong
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiomyocyte
pressure overload
proliferation
right ventricle
RNA‐seq
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.015574

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