Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based study

Background: Chronic pain is prevalent in Sweden, nearing 20% in the adult population. Treatment often requires a multimodal approach, with medication, physical therapy and psychological interventions. However, the frequency of medication in patients with chronic pain in Sweden, and its correlation w...

Full description

Bibliographic Details
Main Authors: Thomas F. Kallman, Emmanuel Bäckryd
Format: Article
Language:English
Published: Medical Journals Sweden 2020-11-01
Series:Journal of Rehabilitation Medicine
Subjects:
Online Access: https://www.medicaljournals.se/jrm/content/html/10.2340/16501977-2758
_version_ 1828750714522828800
author Thomas F. Kallman
Emmanuel Bäckryd
author_facet Thomas F. Kallman
Emmanuel Bäckryd
author_sort Thomas F. Kallman
collection DOAJ
description Background: Chronic pain is prevalent in Sweden, nearing 20% in the adult population. Treatment often requires a multimodal approach, with medication, physical therapy and psychological interventions. However, the frequency of medication in patients with chronic pain in Sweden, and its correlation with patient-reported outcome measures (PROMs), are currently unknown. Objectives: To investigate the frequency of use of analgesics and other medication in patients with chro-nic pain referred to a multidisciplinary pain centre, and how opioid treatment relates to PROMs. Design: Cross-sectional, registry-based study. Patients: New referral visits (n = 1,275) to the Pain and Rehabilitation Center in Linköping, Sweden in 2015. 441 patients had complete medication and PROM data. Methods: Patient-reported analgesic and other medications were matched with patient PROM data from the Swedish Quality Registry for Pain Rehabilitation. Univariate analysis was conducted with IBM Statistical Package for the Social Sciences (SPSS; IBM Corporation, Somers, NY, USA) version 24.0, and multivariate analysis with SIMCA-P+ (version 13, Umetrics AB, Umeå, Sweden), with a special emphasis on opioids. Results: n = 132 (30%) patients used opioids daily, and this group differed from other patients on many PROMs, with medium effect sizes for pain severity, interference, health-related quality of life, activity engagement, and satisfaction with social life. Multivariate analysis identified four groups and showed that daily use of opioids was significantly correlated with high pain intensity and low physical functioning. Conclusion: Prevalence of daily opioid use was 30% and daily opioid use did not correlate with better outcome of PROMs. Longitudinal studies are warranted (e.g. on the clinical effect of tapering), as are studies that can better explain the medication variability in patients with complex chronic pain.
first_indexed 2024-12-10T20:42:26Z
format Article
id doaj.art-c10c4ceedc0a4e0bbeda196dc7d700ae
institution Directory Open Access Journal
issn 1650-1977
1651-2081
language English
last_indexed 2024-12-10T20:42:26Z
publishDate 2020-11-01
publisher Medical Journals Sweden
record_format Article
series Journal of Rehabilitation Medicine
spelling doaj.art-c10c4ceedc0a4e0bbeda196dc7d700ae2022-12-22T01:34:20ZengMedical Journals SwedenJournal of Rehabilitation Medicine1650-19771651-20812020-11-015211jrm0012610.2340/16501977-27582720Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based studyThomas F. Kallman0Emmanuel Bäckryd Pain and Rehabilitation Center, and Department of Health, Medicine and Caring Sciences, Linköping University, SE-581 85 Linköping, Sweden. E-mail: thomas.kallman@liu.se. Background: Chronic pain is prevalent in Sweden, nearing 20% in the adult population. Treatment often requires a multimodal approach, with medication, physical therapy and psychological interventions. However, the frequency of medication in patients with chronic pain in Sweden, and its correlation with patient-reported outcome measures (PROMs), are currently unknown. Objectives: To investigate the frequency of use of analgesics and other medication in patients with chro-nic pain referred to a multidisciplinary pain centre, and how opioid treatment relates to PROMs. Design: Cross-sectional, registry-based study. Patients: New referral visits (n = 1,275) to the Pain and Rehabilitation Center in Linköping, Sweden in 2015. 441 patients had complete medication and PROM data. Methods: Patient-reported analgesic and other medications were matched with patient PROM data from the Swedish Quality Registry for Pain Rehabilitation. Univariate analysis was conducted with IBM Statistical Package for the Social Sciences (SPSS; IBM Corporation, Somers, NY, USA) version 24.0, and multivariate analysis with SIMCA-P+ (version 13, Umetrics AB, Umeå, Sweden), with a special emphasis on opioids. Results: n = 132 (30%) patients used opioids daily, and this group differed from other patients on many PROMs, with medium effect sizes for pain severity, interference, health-related quality of life, activity engagement, and satisfaction with social life. Multivariate analysis identified four groups and showed that daily use of opioids was significantly correlated with high pain intensity and low physical functioning. Conclusion: Prevalence of daily opioid use was 30% and daily opioid use did not correlate with better outcome of PROMs. Longitudinal studies are warranted (e.g. on the clinical effect of tapering), as are studies that can better explain the medication variability in patients with complex chronic pain. https://www.medicaljournals.se/jrm/content/html/10.2340/16501977-2758 chronic pain opioid analgesics multidisciplinary pain rehabilitation sqrp multivariate analysis.
spellingShingle Thomas F. Kallman
Emmanuel Bäckryd
Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based study
Journal of Rehabilitation Medicine
chronic pain
opioid analgesics
multidisciplinary pain rehabilitation
sqrp
multivariate analysis.
title Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based study
title_full Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based study
title_fullStr Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based study
title_full_unstemmed Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based study
title_short Prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient-reported outcome measures: A cross-sectional, registry-based study
title_sort prevalence of analgesic use in patients with chronic pain referred to a multidisciplinary pain centre and its correlation with patient reported outcome measures a cross sectional registry based study
topic chronic pain
opioid analgesics
multidisciplinary pain rehabilitation
sqrp
multivariate analysis.
url https://www.medicaljournals.se/jrm/content/html/10.2340/16501977-2758
work_keys_str_mv AT thomasfkallman prevalenceofanalgesicuseinpatientswithchronicpainreferredtoamultidisciplinarypaincentreanditscorrelationwithpatientreportedoutcomemeasuresacrosssectionalregistrybasedstudy
AT emmanuelbackryd prevalenceofanalgesicuseinpatientswithchronicpainreferredtoamultidisciplinarypaincentreanditscorrelationwithpatientreportedoutcomemeasuresacrosssectionalregistrybasedstudy