Blood-brain barrier permeability following conventional photon radiotherapy – A systematic review and meta-analysis of clinical and preclinical studies
Radiotherapy (RT) is a cornerstone treatment strategy for brain tumours. Besides cytotoxicity, RT can cause disruption of the blood–brain barrier (BBB), resulting in an increased permeability into the surrounding brain parenchyma. Although this effect is generally acknowledged, it remains unclear ho...
Main Authors: | Elvin't Hart, Zelda Odé, Marc P.P. Derieppe, Lucianne Groenink, Martijn W. Heymans, René Otten, Maarten H. Lequin, Geert O.R. Janssens, Eelco W. Hoving, Dannis G. van Vuurden |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-07-01
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Series: | Clinical and Translational Radiation Oncology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405630822000362 |
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