Co-Treatment with Human Leukocyte Extract and Albendazole Stimulates Drug’s Efficacy and Th1 Biased Immune Response in <i>Mesocestoides vogae</i> (Cestoda) Infection via Modulation of Transcription Factors, Macrophage Polarization, and Cytokine Profiles

Co-Treatment with Human Leukocyte Extract and Albendazole Stimulates Drug’s Efficacy and Th1 Biased Immune Response in <i>Mesocestoides vogae</i> (Cestoda) Infection via Modulation of Transcription Factors, Macrophage Polarization, and Cytokine Profiles

The model flatworm <i>Mesocestoides vogae</i> proliferating stage of infection elicits immunosuppression in the host. It was used to investigate the effects of human leukocyte extract (DLE) alone and in combination with anthelmintic albendazole (ABZ) on the reduction in peritoneal infect...

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Bibliographic Details
Main Authors: Gabriela Hrčková, Terézia Mačak Kubašková, Dagmar Mudroňová, Zuzana Jurčacková, Denisa Ciglanová
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
albendazole
DLE
treatment
cestode infection
mice
macrophages
Online Access:https://www.mdpi.com/1999-4923/15/2/541

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