An optimal control model for Covid-19 spread with impacts of vaccination and facemask

A non-linear system of differential equations was used to explain the spread of the COVID-19 virus and a SEIQR model was developed and tested to provide insights into the spread of the pandemic. This article, which is related to the aforementioned work as well as other work covering variations of SI...

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Main Authors: Ammar ElHassan, Yousef AbuHour, Ashraf Ahmad
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023070561
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author Ammar ElHassan
Yousef AbuHour
Ashraf Ahmad
author_facet Ammar ElHassan
Yousef AbuHour
Ashraf Ahmad
author_sort Ammar ElHassan
collection DOAJ
description A non-linear system of differential equations was used to explain the spread of the COVID-19 virus and a SEIQR model was developed and tested to provide insights into the spread of the pandemic. This article, which is related to the aforementioned work as well as other work covering variations of SIR models, Hermite Wavelets Transform, and also the Generalized Compartmental COVID-19 model, we develop a mathematical control model and apply it to represent optimal vaccination strategy against COVID-19 using Pontryagin's Maximum Principle and also factoring in the effect of facemasks on the spread of the virus. As background work, we analyze the mathematical epidemiology model with the facemask effect on both reproduction number and stability, we also analyze the difference between confirmed COVID-19 cases of the Quarantine class and anonymous cases of the Infectious class that is expected to recover. We also apply control theory to mine insights for effective virus spread prevention strategies. Our models are validated using Matlab mathematical model validation tools. Statistical tests against data from Jordan are used to validate our work including the modeling of the relation between the facemask effect and COVID-19 spread. Furthermore, the relation between control measure ξ, cost, and Infected cases is also studied.
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spelling doaj.art-c1113a2017114d749921f8a4183126142023-10-01T06:01:30ZengElsevierHeliyon2405-84402023-09-0199e19848An optimal control model for Covid-19 spread with impacts of vaccination and facemaskAmmar ElHassan0Yousef AbuHour1Ashraf Ahmad2Princess Sumaya University for Technology, Al-Jubaiha, Amman 11941, Amman, 1438, JordanCorresponding author.; Princess Sumaya University for Technology, Al-Jubaiha, Amman 11941, Amman, 1438, JordanPrincess Sumaya University for Technology, Al-Jubaiha, Amman 11941, Amman, 1438, JordanA non-linear system of differential equations was used to explain the spread of the COVID-19 virus and a SEIQR model was developed and tested to provide insights into the spread of the pandemic. This article, which is related to the aforementioned work as well as other work covering variations of SIR models, Hermite Wavelets Transform, and also the Generalized Compartmental COVID-19 model, we develop a mathematical control model and apply it to represent optimal vaccination strategy against COVID-19 using Pontryagin's Maximum Principle and also factoring in the effect of facemasks on the spread of the virus. As background work, we analyze the mathematical epidemiology model with the facemask effect on both reproduction number and stability, we also analyze the difference between confirmed COVID-19 cases of the Quarantine class and anonymous cases of the Infectious class that is expected to recover. We also apply control theory to mine insights for effective virus spread prevention strategies. Our models are validated using Matlab mathematical model validation tools. Statistical tests against data from Jordan are used to validate our work including the modeling of the relation between the facemask effect and COVID-19 spread. Furthermore, the relation between control measure ξ, cost, and Infected cases is also studied.http://www.sciencedirect.com/science/article/pii/S2405844023070561Covid-19Compartmental modelControl modelSpread rateOrdinary differential equationsFacemask
spellingShingle Ammar ElHassan
Yousef AbuHour
Ashraf Ahmad
An optimal control model for Covid-19 spread with impacts of vaccination and facemask
Heliyon
Covid-19
Compartmental model
Control model
Spread rate
Ordinary differential equations
Facemask
title An optimal control model for Covid-19 spread with impacts of vaccination and facemask
title_full An optimal control model for Covid-19 spread with impacts of vaccination and facemask
title_fullStr An optimal control model for Covid-19 spread with impacts of vaccination and facemask
title_full_unstemmed An optimal control model for Covid-19 spread with impacts of vaccination and facemask
title_short An optimal control model for Covid-19 spread with impacts of vaccination and facemask
title_sort optimal control model for covid 19 spread with impacts of vaccination and facemask
topic Covid-19
Compartmental model
Control model
Spread rate
Ordinary differential equations
Facemask
url http://www.sciencedirect.com/science/article/pii/S2405844023070561
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