Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites
Serv The efficacy and safety of sublingual immunotherapy (SLIT) was assessed in patients from Previsora Camagüey Clinic, who were diagnosed with allergic rhinitis and asthma. A retrospective case-control study was carried out. Cases and controls were selected in 62 children from 6 to 24 months of ag...
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| Format: | Article |
| Language: | English |
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Finlay Ediciones
2015-11-01
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| Series: | VacciMonitor |
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| Online Access: | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-028X2015000200005&lng=es&nrm=iso&tlng=es |
| _version_ | 1819178868879130624 |
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| author | Olimpio Rodríguez-Santos María del Carmen Reyes-Almaguer |
| author_facet | Olimpio Rodríguez-Santos María del Carmen Reyes-Almaguer |
| author_sort | Olimpio Rodríguez-Santos |
| collection | DOAJ |
| description | Serv The efficacy and safety of sublingual immunotherapy (SLIT) was assessed in patients from Previsora Camagüey Clinic, who were diagnosed with allergic rhinitis and asthma. A retrospective case-control study was carried out. Cases and controls were selected in 62 children from 6 to 24 months of age: 34 children had used ITSL (cases); the other 28 children received only environmental prevention (controls). All children used medicines in the crisis stage. Quality of life questionnaires for rhinitis (RQLQm) and asthma (AQLQm) were applied. Medicine consumption and frequency of crises were analyzed. A subjective assessment of children health before and after the treatment was performed to relatives and physicians. Local and systemic reactions to SLIT were evaluated. An increase in the score of life quality questionnaires was detected (p=0.033). The medicine consumption was more reduced in cases than in controls (p=0.003). The frequency of respiratory symptomatology decreased (p=0.029). The score of subjective assessment was negative before treatment. After the treatment 85% of cases got 5 points, while the remaining 15% of cases obtained between 3 and 4 points. In the control group 55% of patients obtained 5 points, 10% of evaluated children between 3 and 4, and 5% between 0 and 2 points (p=0.011). Two mild adverse reactions to the SLIT were reported. Results showed that the sublingual immunotherapy with mites in children under 2 years old with rhinitis and asthma is effective and safe |
| first_indexed | 2024-12-22T21:49:24Z |
| format | Article |
| id | doaj.art-c1121644df22404ca8941854d82cb16a |
| institution | Directory Open Access Journal |
| issn | 1025-028X 1025-0298 |
| language | English |
| last_indexed | 2024-12-22T21:49:24Z |
| publishDate | 2015-11-01 |
| publisher | Finlay Ediciones |
| record_format | Article |
| series | VacciMonitor |
| spelling | doaj.art-c1121644df22404ca8941854d82cb16a2022-12-21T18:11:24ZengFinlay EdicionesVacciMonitor1025-028X1025-02982015-11-012428692Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites Olimpio Rodríguez-Santos0María del Carmen Reyes-Almaguer1Servicio Alergia Policlínico Universitario Docente, Previsora, Camagüey, CubaServicio Alergia Policlínico Universitario Docente, Previsora, Camagüey, CubaServ The efficacy and safety of sublingual immunotherapy (SLIT) was assessed in patients from Previsora Camagüey Clinic, who were diagnosed with allergic rhinitis and asthma. A retrospective case-control study was carried out. Cases and controls were selected in 62 children from 6 to 24 months of age: 34 children had used ITSL (cases); the other 28 children received only environmental prevention (controls). All children used medicines in the crisis stage. Quality of life questionnaires for rhinitis (RQLQm) and asthma (AQLQm) were applied. Medicine consumption and frequency of crises were analyzed. A subjective assessment of children health before and after the treatment was performed to relatives and physicians. Local and systemic reactions to SLIT were evaluated. An increase in the score of life quality questionnaires was detected (p=0.033). The medicine consumption was more reduced in cases than in controls (p=0.003). The frequency of respiratory symptomatology decreased (p=0.029). The score of subjective assessment was negative before treatment. After the treatment 85% of cases got 5 points, while the remaining 15% of cases obtained between 3 and 4 points. In the control group 55% of patients obtained 5 points, 10% of evaluated children between 3 and 4, and 5% between 0 and 2 points (p=0.011). Two mild adverse reactions to the SLIT were reported. Results showed that the sublingual immunotherapy with mites in children under 2 years old with rhinitis and asthma is effective and safehttp://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-028X2015000200005&lng=es&nrm=iso&tlng=essublingual immunotherapylife qualityasthma; rhinitis |
| spellingShingle | Olimpio Rodríguez-Santos María del Carmen Reyes-Almaguer Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites VacciMonitor sublingual immunotherapy life quality asthma; rhinitis |
| title | Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites |
| title_full | Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites |
| title_fullStr | Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites |
| title_full_unstemmed | Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites |
| title_short | Efficacy and safety of sublingual immunotherapy in children aged 6-24 months with rhinitis and bronchial asthma sensitized to house dust mites |
| title_sort | efficacy and safety of sublingual immunotherapy in children aged 6 24 months with rhinitis and bronchial asthma sensitized to house dust mites |
| topic | sublingual immunotherapy life quality asthma; rhinitis |
| url | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-028X2015000200005&lng=es&nrm=iso&tlng=es |
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