A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury

Bibliographic Details
Main Authors: Joshua J. Woods, Neeharika Nemani, Santhanam Shanmughapriya, Akshay Kumar, MengQi Zhang, Sarah R. Nathan, Manfred Thomas, Edmund Carvalho, Karthik Ramachandran, Subramanya Srikantan, Peter B. Stathopulos, Justin J. Wilson, Muniswamy Madesh
Format: Article
Language:English
Published: American Chemical Society 2019-01-01
Series:ACS Central Science
Online Access:https://doi.org/10.1021/acscentsci.8b00773
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author Joshua J. Woods
Neeharika Nemani
Santhanam Shanmughapriya
Akshay Kumar
MengQi Zhang
Sarah R. Nathan
Manfred Thomas
Edmund Carvalho
Karthik Ramachandran
Subramanya Srikantan
Peter B. Stathopulos
Justin J. Wilson
Muniswamy Madesh
author_facet Joshua J. Woods
Neeharika Nemani
Santhanam Shanmughapriya
Akshay Kumar
MengQi Zhang
Sarah R. Nathan
Manfred Thomas
Edmund Carvalho
Karthik Ramachandran
Subramanya Srikantan
Peter B. Stathopulos
Justin J. Wilson
Muniswamy Madesh
author_sort Joshua J. Woods
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publishDate 2019-01-01
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spelling doaj.art-c11a3ac499984fe6bac920a1430a48432022-12-21T23:10:58ZengAmerican Chemical SocietyACS Central Science2374-79512019-01-015115316610.1021/acscentsci.8b00773A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation InjuryJoshua J. Woods0Neeharika Nemani1Santhanam Shanmughapriya2Akshay Kumar3MengQi Zhang4Sarah R. Nathan5Manfred Thomas6Edmund Carvalho7Karthik Ramachandran8Subramanya Srikantan9Peter B. Stathopulos10Justin J. Wilson11Muniswamy Madesh12Robert F. Smith School for Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York, United StatesDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United StatesDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United StatesDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United StatesDepartment of Physiology and Pharmacology, Western University, London, Ontario, CanadaDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United StatesDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United StatesDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United StatesDepartment of Medicine/Nephrology, Institute for Precision Medicine and Health, University of Texas Health San Antonio, San Antonio, Texas, United StatesDepartment of Medicine/Nephrology, Institute for Precision Medicine and Health, University of Texas Health San Antonio, San Antonio, Texas, United StatesDepartment of Physiology and Pharmacology, Western University, London, Ontario, CanadaDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, United StatesDepartment of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, United Stateshttps://doi.org/10.1021/acscentsci.8b00773
spellingShingle Joshua J. Woods
Neeharika Nemani
Santhanam Shanmughapriya
Akshay Kumar
MengQi Zhang
Sarah R. Nathan
Manfred Thomas
Edmund Carvalho
Karthik Ramachandran
Subramanya Srikantan
Peter B. Stathopulos
Justin J. Wilson
Muniswamy Madesh
A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
ACS Central Science
title A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
title_full A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
title_fullStr A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
title_full_unstemmed A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
title_short A Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury
title_sort selective and cell permeable mitochondrial calcium uniporter mcu inhibitor preserves mitochondrial bioenergetics after hypoxia reoxygenation injury
url https://doi.org/10.1021/acscentsci.8b00773
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