A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence
Characterizing HIV acquisition modes among adolescents with HIV (AHIV) enrolling in care during adolescence is a challenging gap that impacts differential interventions. We explored whether primary data collection with targeted questionnaires may address this gap and improve understanding of risk fa...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-05-01
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| Series: | Global Pediatric Health |
| Online Access: | https://doi.org/10.1177/2333794X221101768 |
| _version_ | 1817989241329680384 |
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| author | John Humphrey MD Miranda Triedman BS Winstone Nyandiko MBChB, MMed Edwin Sang MS Emmanuel Kemboi BS Marsha Alera MS Vlad Novitsky MD, PhD Akarsh Manne MS Eslyne Jepkemboi BS Millicent Orido BS Edith Apondi MBChB, MMed Rachel Vreeman MD Kara Wools-Kaloustian MD Rami Kantor MD |
| author_facet | John Humphrey MD Miranda Triedman BS Winstone Nyandiko MBChB, MMed Edwin Sang MS Emmanuel Kemboi BS Marsha Alera MS Vlad Novitsky MD, PhD Akarsh Manne MS Eslyne Jepkemboi BS Millicent Orido BS Edith Apondi MBChB, MMed Rachel Vreeman MD Kara Wools-Kaloustian MD Rami Kantor MD |
| author_sort | John Humphrey MD |
| collection | DOAJ |
| description | Characterizing HIV acquisition modes among adolescents with HIV (AHIV) enrolling in care during adolescence is a challenging gap that impacts differential interventions. We explored whether primary data collection with targeted questionnaires may address this gap and improve understanding of risk factors and perceptions about adolescents’ HIV acquisition, in Kenyan AHIV entering care at ≥10 years, and their mothers with HIV (MHIV). Clinical data were derived through chart review. Among 1073 AHIV in care, only 26 (2%) met eligibility criteria of being ≥10 years at care enrollment, disclosed to, and with living MHIV. Among 18/26 AHIV-MHIV dyads enrolled (median age of AHIV 14 years), none had documented HIV acquisition modes. Data suggested perinatal infection in 17/18 AHIV, with 1 reported non-perinatal acquisition risk factor, and some discordance between adolescent-mother perceptions of HIV acquisition. In this difficult-to-enroll, vulnerable population of AHIV-MHIV dyads, primary data collection can enhance understanding of AHIV acquisition modes. |
| first_indexed | 2024-04-14T00:44:40Z |
| format | Article |
| id | doaj.art-c11a6e58e28f4a8d926a8dca2caba445 |
| institution | Directory Open Access Journal |
| issn | 2333-794X |
| language | English |
| last_indexed | 2024-04-14T00:44:40Z |
| publishDate | 2022-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Global Pediatric Health |
| spelling | doaj.art-c11a6e58e28f4a8d926a8dca2caba4452022-12-22T02:22:05ZengSAGE PublishingGlobal Pediatric Health2333-794X2022-05-01910.1177/2333794X221101768A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During AdolescenceJohn Humphrey MD0Miranda Triedman BS1Winstone Nyandiko MBChB, MMed2Edwin Sang MS3Emmanuel Kemboi BS4Marsha Alera MS5Vlad Novitsky MD, PhD6Akarsh Manne MS7Eslyne Jepkemboi BS8Millicent Orido BS9Edith Apondi MBChB, MMed10Rachel Vreeman MD11Kara Wools-Kaloustian MD12Rami Kantor MD13Indiana University, Indianapolis, IN, USABrown University, Providence, RI, USAAcademic Model Providing Access to Healthcare, Eldoret, KenyaAcademic Model Providing Access to Healthcare, Eldoret, KenyaAcademic Model Providing Access to Healthcare, Eldoret, KenyaAcademic Model Providing Access to Healthcare, Eldoret, KenyaBrown University, Providence, RI, USABrown University, Providence, RI, USAAcademic Model Providing Access to Healthcare, Eldoret, KenyaAcademic Model Providing Access to Healthcare, Eldoret, KenyaMoi Teaching and Referral Hospital, Eldoret, KenyaIcahn School of Medicine at Mount Sinai, New York, NY, USAIndiana University, Indianapolis, IN, USABrown University, Providence, RI, USACharacterizing HIV acquisition modes among adolescents with HIV (AHIV) enrolling in care during adolescence is a challenging gap that impacts differential interventions. We explored whether primary data collection with targeted questionnaires may address this gap and improve understanding of risk factors and perceptions about adolescents’ HIV acquisition, in Kenyan AHIV entering care at ≥10 years, and their mothers with HIV (MHIV). Clinical data were derived through chart review. Among 1073 AHIV in care, only 26 (2%) met eligibility criteria of being ≥10 years at care enrollment, disclosed to, and with living MHIV. Among 18/26 AHIV-MHIV dyads enrolled (median age of AHIV 14 years), none had documented HIV acquisition modes. Data suggested perinatal infection in 17/18 AHIV, with 1 reported non-perinatal acquisition risk factor, and some discordance between adolescent-mother perceptions of HIV acquisition. In this difficult-to-enroll, vulnerable population of AHIV-MHIV dyads, primary data collection can enhance understanding of AHIV acquisition modes.https://doi.org/10.1177/2333794X221101768 |
| spellingShingle | John Humphrey MD Miranda Triedman BS Winstone Nyandiko MBChB, MMed Edwin Sang MS Emmanuel Kemboi BS Marsha Alera MS Vlad Novitsky MD, PhD Akarsh Manne MS Eslyne Jepkemboi BS Millicent Orido BS Edith Apondi MBChB, MMed Rachel Vreeman MD Kara Wools-Kaloustian MD Rami Kantor MD A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence Global Pediatric Health |
| title | A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence |
| title_full | A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence |
| title_fullStr | A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence |
| title_full_unstemmed | A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence |
| title_short | A Challenging Knowledge Gap: Estimating Modes of HIV Acquisition Among Adolescents Entering HIV Care During Adolescence |
| title_sort | challenging knowledge gap estimating modes of hiv acquisition among adolescents entering hiv care during adolescence |
| url | https://doi.org/10.1177/2333794X221101768 |
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