Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold Paralysis
This article addresses the potential clinical value of surface electrical stimulation in the acute phase of denervation after the onset of facial nerve or recurrent laryngeal nerve paralysis. These two nerve lesions are the most frequent head and neck nerve lesions. In this review, we will work out...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-04-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.869900/full |
| _version_ | 1811284742910246912 |
|---|---|
| author | Annabella Kurz Gerd Fabian Volk Gerd Fabian Volk Gerd Fabian Volk Dirk Arnold Dirk Arnold Berit Schneider-Stickler Winfried Mayr Orlando Guntinas-Lichius Orlando Guntinas-Lichius Orlando Guntinas-Lichius |
| author_facet | Annabella Kurz Gerd Fabian Volk Gerd Fabian Volk Gerd Fabian Volk Dirk Arnold Dirk Arnold Berit Schneider-Stickler Winfried Mayr Orlando Guntinas-Lichius Orlando Guntinas-Lichius Orlando Guntinas-Lichius |
| author_sort | Annabella Kurz |
| collection | DOAJ |
| description | This article addresses the potential clinical value of surface electrical stimulation in the acute phase of denervation after the onset of facial nerve or recurrent laryngeal nerve paralysis. These two nerve lesions are the most frequent head and neck nerve lesions. In this review, we will work out several similarities concerning the pathophysiology features and the clinical scenario between both nerve lesions, which allow to develop some general rules for surface electrical stimulation applicable for both nerve lesions. The focus is on electrical stimulation in the phase between denervation and reinnervation of the target muscles. The aim of electrostimulation in this phase of denervation is to bridge the time until reinnervation is complete and to maintain facial or laryngeal function. In this phase, electrostimulation has to stimulate directly the denervated muscles, i.e. muscle stimulation and not nerve stimulation. There is preliminary data that early electrostimulation might also improve the functional outcome. Because there are still caveats against the use of electrostimulation, the neurophysiology of denervated facial and laryngeal muscles in comparison to innervated muscles is explained in detail. This is necessary to understand why the negative results published in several studies that used stimulation parameters are not suitable for denervated muscle fibers. Juxtaposed are studies using parameters adapted for the stimulation of denervated facial or laryngeal muscles. These studies used standardized outcome measure and show that an effective and tolerable electrostimulation of facial and laryngeal muscles without side effects in the early phase after onset of the lesions is feasible, does not hinder nerve regeneration and might even be able to improve the functional outcome. This has now to be proven in larger controlled trials. In our view, surface electrical stimulation has an unexploited potential to enrich the early therapy concepts for patients with unilateral facial or vocal fold paralysis. |
| first_indexed | 2024-04-13T02:33:31Z |
| format | Article |
| id | doaj.art-c1213c00f882438fb4c10740f9248b1a |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-13T02:33:31Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-c1213c00f882438fb4c10740f9248b1a2022-12-22T03:06:28ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-04-011310.3389/fneur.2022.869900869900Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold ParalysisAnnabella Kurz0Gerd Fabian Volk1Gerd Fabian Volk2Gerd Fabian Volk3Dirk Arnold4Dirk Arnold5Berit Schneider-Stickler6Winfried Mayr7Orlando Guntinas-Lichius8Orlando Guntinas-Lichius9Orlando Guntinas-Lichius10Department of Otorhinolaryngology, Division of Phoniatrics-Logopedics, Medical University of Vienna, Vienna, AustriaDepartment of Otorhinolaryngology, Jena University Hospital, Jena, GermanyFacial-Nerve-Center Jena, Jena University Hospital, Jena, GermanyCenter for Rare Diseases, Jena University Hospital, Jena, GermanyDepartment of Otorhinolaryngology, Jena University Hospital, Jena, GermanyFacial-Nerve-Center Jena, Jena University Hospital, Jena, GermanyDepartment of Otorhinolaryngology, Division of Phoniatrics-Logopedics, Medical University of Vienna, Vienna, AustriaCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, AustriaDepartment of Otorhinolaryngology, Jena University Hospital, Jena, GermanyFacial-Nerve-Center Jena, Jena University Hospital, Jena, GermanyCenter for Rare Diseases, Jena University Hospital, Jena, GermanyThis article addresses the potential clinical value of surface electrical stimulation in the acute phase of denervation after the onset of facial nerve or recurrent laryngeal nerve paralysis. These two nerve lesions are the most frequent head and neck nerve lesions. In this review, we will work out several similarities concerning the pathophysiology features and the clinical scenario between both nerve lesions, which allow to develop some general rules for surface electrical stimulation applicable for both nerve lesions. The focus is on electrical stimulation in the phase between denervation and reinnervation of the target muscles. The aim of electrostimulation in this phase of denervation is to bridge the time until reinnervation is complete and to maintain facial or laryngeal function. In this phase, electrostimulation has to stimulate directly the denervated muscles, i.e. muscle stimulation and not nerve stimulation. There is preliminary data that early electrostimulation might also improve the functional outcome. Because there are still caveats against the use of electrostimulation, the neurophysiology of denervated facial and laryngeal muscles in comparison to innervated muscles is explained in detail. This is necessary to understand why the negative results published in several studies that used stimulation parameters are not suitable for denervated muscle fibers. Juxtaposed are studies using parameters adapted for the stimulation of denervated facial or laryngeal muscles. These studies used standardized outcome measure and show that an effective and tolerable electrostimulation of facial and laryngeal muscles without side effects in the early phase after onset of the lesions is feasible, does not hinder nerve regeneration and might even be able to improve the functional outcome. This has now to be proven in larger controlled trials. In our view, surface electrical stimulation has an unexploited potential to enrich the early therapy concepts for patients with unilateral facial or vocal fold paralysis.https://www.frontiersin.org/articles/10.3389/fneur.2022.869900/fullelectrical stimulationfacial nervevagal nerverecurrent laryngeal nervenerve stimulationmuscle stimulation |
| spellingShingle | Annabella Kurz Gerd Fabian Volk Gerd Fabian Volk Gerd Fabian Volk Dirk Arnold Dirk Arnold Berit Schneider-Stickler Winfried Mayr Orlando Guntinas-Lichius Orlando Guntinas-Lichius Orlando Guntinas-Lichius Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold Paralysis Frontiers in Neurology electrical stimulation facial nerve vagal nerve recurrent laryngeal nerve nerve stimulation muscle stimulation |
| title | Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold Paralysis |
| title_full | Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold Paralysis |
| title_fullStr | Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold Paralysis |
| title_full_unstemmed | Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold Paralysis |
| title_short | Selective Electrical Surface Stimulation to Support Functional Recovery in the Early Phase After Unilateral Acute Facial Nerve or Vocal Fold Paralysis |
| title_sort | selective electrical surface stimulation to support functional recovery in the early phase after unilateral acute facial nerve or vocal fold paralysis |
| topic | electrical stimulation facial nerve vagal nerve recurrent laryngeal nerve nerve stimulation muscle stimulation |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.869900/full |
| work_keys_str_mv | AT annabellakurz selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT gerdfabianvolk selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT gerdfabianvolk selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT gerdfabianvolk selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT dirkarnold selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT dirkarnold selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT beritschneiderstickler selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT winfriedmayr selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT orlandoguntinaslichius selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT orlandoguntinaslichius selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis AT orlandoguntinaslichius selectiveelectricalsurfacestimulationtosupportfunctionalrecoveryintheearlyphaseafterunilateralacutefacialnerveorvocalfoldparalysis |