Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report
Abstract Background Transverse myelitis (TM) is characterized by acute development of motor, sensory and autonomic dysfunctions due to horizontally diffused inflammation in one or more segments of the spinal cord in the absence of a compressive lesion. The not well-known inflammation process induces...
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | BMC Neurology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12883-022-02881-1 |
| _version_ | 1811335394627682304 |
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| author | Juan Esteban Oyarzún Raúl Caulier-Cisterna Juan Pablo González-Appelgren Leticia Gonzalez Oscar Trujillo Antonio Eblen-Zajjur Sergio Uribe |
| author_facet | Juan Esteban Oyarzún Raúl Caulier-Cisterna Juan Pablo González-Appelgren Leticia Gonzalez Oscar Trujillo Antonio Eblen-Zajjur Sergio Uribe |
| author_sort | Juan Esteban Oyarzún |
| collection | DOAJ |
| description | Abstract Background Transverse myelitis (TM) is characterized by acute development of motor, sensory and autonomic dysfunctions due to horizontally diffused inflammation in one or more segments of the spinal cord in the absence of a compressive lesion. The not well-known inflammation process induces demyelination resulting in neurological dysfunction. Case presentation In this case report we used a functional Near-Infrared Spectroscopy (fNIRS) technique to evaluate changes in the peri-spinal vascular response induced by a peripheral median nerve electrical stimulation in a patient with chronic transverse myelitis (TM). fNIRS showed drastically reduced signal amplitude in the peri-spinal vascular response, compared to that obtained from a healthy control group throughout most of the C7-T1 and T10-L2 spinal cord segments. Conclusion The potential use of this relatively non-invasive fNIRS technology support the potential clinical application of this method for functional test of the spinal cord through the assessment of the spinal neurovascular response. |
| first_indexed | 2024-04-13T17:23:26Z |
| format | Article |
| id | doaj.art-c124787cadc044d997d46032235232f9 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-04-13T17:23:26Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-c124787cadc044d997d46032235232f92022-12-22T02:37:53ZengBMCBMC Neurology1471-23772022-10-012211510.1186/s12883-022-02881-1Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case reportJuan Esteban Oyarzún0Raúl Caulier-Cisterna1Juan Pablo González-Appelgren2Leticia Gonzalez3Oscar Trujillo4Antonio Eblen-Zajjur5Sergio Uribe6Centro de Imágenes Biomédicas, Pontificia Universidad Católica de ChileCentro de Imágenes Biomédicas, Pontificia Universidad Católica de ChileCentro de Imágenes Biomédicas, Pontificia Universidad Católica de ChileCentro de Imágenes Biomédicas, Pontificia Universidad Católica de ChileNeurology Department, School of Medicine, Pontificia Universidad Católica de ChileLaboratorio de Neurociencia Traslacional, Facultad de Medicina, Universidad Diego Portales SantiagoCentro de Imágenes Biomédicas, Pontificia Universidad Católica de ChileAbstract Background Transverse myelitis (TM) is characterized by acute development of motor, sensory and autonomic dysfunctions due to horizontally diffused inflammation in one or more segments of the spinal cord in the absence of a compressive lesion. The not well-known inflammation process induces demyelination resulting in neurological dysfunction. Case presentation In this case report we used a functional Near-Infrared Spectroscopy (fNIRS) technique to evaluate changes in the peri-spinal vascular response induced by a peripheral median nerve electrical stimulation in a patient with chronic transverse myelitis (TM). fNIRS showed drastically reduced signal amplitude in the peri-spinal vascular response, compared to that obtained from a healthy control group throughout most of the C7-T1 and T10-L2 spinal cord segments. Conclusion The potential use of this relatively non-invasive fNIRS technology support the potential clinical application of this method for functional test of the spinal cord through the assessment of the spinal neurovascular response.https://doi.org/10.1186/s12883-022-02881-1Near infrared spectroscopy (NIRS)Spinal neurovascular responseNon-invasive methodTransverse myelitisSpinal neuronal activityNeuron-vascular coupling |
| spellingShingle | Juan Esteban Oyarzún Raúl Caulier-Cisterna Juan Pablo González-Appelgren Leticia Gonzalez Oscar Trujillo Antonio Eblen-Zajjur Sergio Uribe Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report BMC Neurology Near infrared spectroscopy (NIRS) Spinal neurovascular response Non-invasive method Transverse myelitis Spinal neuronal activity Neuron-vascular coupling |
| title | Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report |
| title_full | Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report |
| title_fullStr | Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report |
| title_full_unstemmed | Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report |
| title_short | Non-invasive near-infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis: a case report |
| title_sort | non invasive near infrared spectroscopy assessment of the spinal neurovascular response in a patient with transverse myelitis a case report |
| topic | Near infrared spectroscopy (NIRS) Spinal neurovascular response Non-invasive method Transverse myelitis Spinal neuronal activity Neuron-vascular coupling |
| url | https://doi.org/10.1186/s12883-022-02881-1 |
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