Innate Immune Response Regulation by the Human RNASET2 Tumor Suppressor Gene

Innate Immune Response Regulation by the Human RNASET2 Tumor Suppressor Gene

The link between cancer development or progression and immune system dysregulation has long been established. Virtually every cell type belonging to both the innate and adaptive immune system has been reported to be involved in a complex interplay that might culminate into either a pro- or anti-tumo...

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Bibliographic Details
Main Authors: Francesco Acquati, Lorenzo Mortara, Annarosaria De Vito, Denisa Baci, Adriana Albini, Marco Cippitelli, Roberto Taramelli, Douglas M. Noonan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
T2 RNases
innate immune response
tumor suppression
stress response
tumor microenvironment
targeting immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02587/full

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