PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer

PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer

p53 is a common tumor suppressor, and its mutation drives tumorigenesis. What is more, p53 mutations have also been reported to be indicative of poor prognosis in lung cancer, but the detailed mechanism has not been elucidated. In this study, we found that DNA primase subunit 2 (PRIM2) had a high ex...

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Bibliographic Details
Main Authors: Taoyuan Wang, Tiansheng Tang, Youguo Jiang, Tao He, Luyu Qi, Hongkai Chang, Yaya Qiao, Mingming Sun, Changliang Shan, Xinyuan Zhu, Jianshi Liu, Jiyan Wang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
p53 mutation
cell cycle
mismatch repair
PRIM2
lung cancer
Online Access:https://www.mdpi.com/2072-6694/14/14/3370

Internet

https://www.mdpi.com/2072-6694/14/14/3370

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