Protective Effects of Eicosapentaenoic Acid Plus Hydroxytyrosol Supplementation Against White Adipose Tissue Abnormalities in Mice Fed a High-Fat Diet

Protective Effects of Eicosapentaenoic Acid Plus Hydroxytyrosol Supplementation Against White Adipose Tissue Abnormalities in Mice Fed a High-Fat Diet

Objective: Obesity induced by high-fat diet (HFD) elicits white adipose tissue dysfunction. In this study, we have hypothesized that the metabolic modulator eicosapentaenoic acid (EPA) combined with the antioxidant hydroxytyrosol (HT) attenuates HFD-induced white adipose tissue (WAT) alterations. Me...

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Bibliographic Details
Main Authors: Paola Illesca, Rodrigo Valenzuela, Alejandra Espinosa, Francisca Echeverría, Sandra Soto-Alarcon, Cristian Campos, Alicia Rodriguez, Romina Vargas, Thea Magrone, Luis A. Videla
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
high-fat diet
white adipose tissue
adipocyte hypertrophy
metabolic dysfunction
eicosapentaenoic acid
hydroxytyrosol
Online Access:https://www.mdpi.com/1420-3049/25/19/4433

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