Characteristics of patients with endometrial hyperplasia under different air quality index conditions
Objective: Air pollution has been widely recognized to pose a threat to health. Urban outdoor air pollution was listed as the 14th biggest risk factor for global deaths in 2004 in the Global Health Risks report published by the World Health Organization in 2009. Many past studies have indicated that...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-03-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S102845591930021X |
| _version_ | 1811227054392213504 |
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| author | Fung-Wei Chang Ren-Jun Hsu Shu-Hui Liu |
| author_facet | Fung-Wei Chang Ren-Jun Hsu Shu-Hui Liu |
| author_sort | Fung-Wei Chang |
| collection | DOAJ |
| description | Objective: Air pollution has been widely recognized to pose a threat to health. Urban outdoor air pollution was listed as the 14th biggest risk factor for global deaths in 2004 in the Global Health Risks report published by the World Health Organization in 2009. Many past studies have indicated that exposure to environmental contaminants promotes changes in the internal mechanisms of diseases, including the infection of various systems in the body, hormonal changes, and vascular proliferation. These changes may be related to the severity of endometrial hyperplasia. Therefore, this study used the air quality monitoring data of the Environmental Protection Administration (EPA) to examine the effects of air pollutant concentration on patients with endometrial hyperplasia. Materials and methods: This population-based nationwide study used data for 2002–2013 from the National Health Insurance Research Database of Taiwan. Patients who developed endometrial hyperplasia before 2002 were excluded. In total, 14,883 patients with endometrial hyperplasia were tracked. The exposure levels and air quality index (AQI) values in this study were based on the taiwan air quality monitoring network data collected by the EPA from 2000 to 2013. The data were further divided into the good air quality group (AQI ≤ 50) and poor air quality group (AQI > 50). The study used linear regression model to estimate the correlation linking air pollutant concentration with endometrial hyperplasia. Results: The results indicated that, in comparison to endometrial hyperplasia patients who were exposed to air with good quality, those exposed to air with poor quality had a higher average age (p < 0.001) and higher proportion of living in southern Taiwan (p < 0.001), as well as higher rates of diabetes (p < 0.001), hyperlipidemia (p < 0.001), hypertension, cerebrovascular diseases (p = 0.024), cerebral vascular accidents (p = 0.024), and chronic kidney disease (p < 0.001). Conclusion: The patients with endometrial hyperplasia in poor AQI area had severe comorbidity. Thus, attention must be paid to the improvement of air quality and the implementation of preventive measures against contaminants. Keywords: Air quality index, Endometrial hyperplasia, Pollution exposure |
| first_indexed | 2024-04-12T09:34:47Z |
| format | Article |
| id | doaj.art-c12c955155ff4158a68398d01e5994b5 |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-04-12T09:34:47Z |
| publishDate | 2019-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-c12c955155ff4158a68398d01e5994b52022-12-22T03:38:15ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592019-03-01582282287Characteristics of patients with endometrial hyperplasia under different air quality index conditionsFung-Wei Chang0Ren-Jun Hsu1Shu-Hui Liu2Department of Obstetrics & Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Superintendent, Tri-Service General Hospital Penghu Branch, National, Defense Medical Center, Penghu Branch, Taiwan; Defence Medical Center, Penghu Branch, TaiwanGraduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan; Cancer Medicine Center of Buddhist Hualien Tzu Chi Hospital, Tzu Chi University, Hualien, Taiwan; Department of Pathology and Graduate Institute of Pathology and Parasitology, The Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDepartment of Health Care and Social Work, Yu Da University of Science and Technology, Miaoli, Taiwan; Department of Leisure Management, Yu Da University of Science and Technology, Miaoli, Taiwan; Corresponding author. Department of Health Care and Social Work, Yu Da University of Science and Technology, 168 Hsueh-fu Rd, Chaochiao Township, Miaoli, 36143, Taiwan. Fax: +886 37 651225.Objective: Air pollution has been widely recognized to pose a threat to health. Urban outdoor air pollution was listed as the 14th biggest risk factor for global deaths in 2004 in the Global Health Risks report published by the World Health Organization in 2009. Many past studies have indicated that exposure to environmental contaminants promotes changes in the internal mechanisms of diseases, including the infection of various systems in the body, hormonal changes, and vascular proliferation. These changes may be related to the severity of endometrial hyperplasia. Therefore, this study used the air quality monitoring data of the Environmental Protection Administration (EPA) to examine the effects of air pollutant concentration on patients with endometrial hyperplasia. Materials and methods: This population-based nationwide study used data for 2002–2013 from the National Health Insurance Research Database of Taiwan. Patients who developed endometrial hyperplasia before 2002 were excluded. In total, 14,883 patients with endometrial hyperplasia were tracked. The exposure levels and air quality index (AQI) values in this study were based on the taiwan air quality monitoring network data collected by the EPA from 2000 to 2013. The data were further divided into the good air quality group (AQI ≤ 50) and poor air quality group (AQI > 50). The study used linear regression model to estimate the correlation linking air pollutant concentration with endometrial hyperplasia. Results: The results indicated that, in comparison to endometrial hyperplasia patients who were exposed to air with good quality, those exposed to air with poor quality had a higher average age (p < 0.001) and higher proportion of living in southern Taiwan (p < 0.001), as well as higher rates of diabetes (p < 0.001), hyperlipidemia (p < 0.001), hypertension, cerebrovascular diseases (p = 0.024), cerebral vascular accidents (p = 0.024), and chronic kidney disease (p < 0.001). Conclusion: The patients with endometrial hyperplasia in poor AQI area had severe comorbidity. Thus, attention must be paid to the improvement of air quality and the implementation of preventive measures against contaminants. Keywords: Air quality index, Endometrial hyperplasia, Pollution exposurehttp://www.sciencedirect.com/science/article/pii/S102845591930021X |
| spellingShingle | Fung-Wei Chang Ren-Jun Hsu Shu-Hui Liu Characteristics of patients with endometrial hyperplasia under different air quality index conditions Taiwanese Journal of Obstetrics & Gynecology |
| title | Characteristics of patients with endometrial hyperplasia under different air quality index conditions |
| title_full | Characteristics of patients with endometrial hyperplasia under different air quality index conditions |
| title_fullStr | Characteristics of patients with endometrial hyperplasia under different air quality index conditions |
| title_full_unstemmed | Characteristics of patients with endometrial hyperplasia under different air quality index conditions |
| title_short | Characteristics of patients with endometrial hyperplasia under different air quality index conditions |
| title_sort | characteristics of patients with endometrial hyperplasia under different air quality index conditions |
| url | http://www.sciencedirect.com/science/article/pii/S102845591930021X |
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