The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 compared

<p>Abstract</p> <p>Background</p> <p>Against a background of interest in rates of diabetes in schizophrenia and related psychoses and claims that data from historical periods demonstrate a link that antedates modern antipsychotics, we sought to establish the rate of dia...

Full description

Bibliographic Details
Main Authors: Roberts Tony, Williams Dawn, Wong Winnie, Harris Margaret, Khan Afshan, Le Noury Joanna, Tranter Richard, Healy David
Format: Article
Language:English
Published: BMC 2008-08-01
Series:BMC Psychiatry
Online Access:http://www.biomedcentral.com/1471-244X/8/67
_version_ 1811252085466857472
author Roberts Tony
Williams Dawn
Wong Winnie
Harris Margaret
Khan Afshan
Le Noury Joanna
Tranter Richard
Healy David
author_facet Roberts Tony
Williams Dawn
Wong Winnie
Harris Margaret
Khan Afshan
Le Noury Joanna
Tranter Richard
Healy David
author_sort Roberts Tony
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Against a background of interest in rates of diabetes in schizophrenia and related psychoses and claims that data from historical periods demonstrate a link that antedates modern antipsychotics, we sought to establish the rate of diabetes in first onset psychosis and subsequent prevalence in historical and contemporary cohorts.</p> <p>Methods</p> <p>Analysis of two epidemiologically complete databases of individuals admitted for mental illness. 3170 individuals admitted to the North Wales Asylum between 1875–1924 and tracked over 18,486 patient years and 394 North West Wales first admissions for schizophrenia and related psychoses between 1994 and 2006 and tracked after treatment.</p> <p>Results</p> <p>The prevalence of Type 2 diabetes among patients with psychoses at time of first admission in both historical and contemporary samples was 0%. The incidence of diabetes remained 0% in the historical sample throughout 15 years of follow-up but rose in the contemporary sample after 3, 5 and 6 years of treatment with an incidence rate double the expected population rate so that the 15 year prevalence is likely to be over 8%.</p> <p>Conclusion</p> <p>No association was found between diabetes and serious mental illness, but there may be an association between diabetes and treatment.</p>
first_indexed 2024-04-12T16:29:34Z
format Article
id doaj.art-c12dde0bb2354c73a2e6a0cf0d276869
institution Directory Open Access Journal
issn 1471-244X
language English
last_indexed 2024-04-12T16:29:34Z
publishDate 2008-08-01
publisher BMC
record_format Article
series BMC Psychiatry
spelling doaj.art-c12dde0bb2354c73a2e6a0cf0d2768692022-12-22T03:25:13ZengBMCBMC Psychiatry1471-244X2008-08-01816710.1186/1471-244X-8-67The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 comparedRoberts TonyWilliams DawnWong WinnieHarris MargaretKhan AfshanLe Noury JoannaTranter RichardHealy David<p>Abstract</p> <p>Background</p> <p>Against a background of interest in rates of diabetes in schizophrenia and related psychoses and claims that data from historical periods demonstrate a link that antedates modern antipsychotics, we sought to establish the rate of diabetes in first onset psychosis and subsequent prevalence in historical and contemporary cohorts.</p> <p>Methods</p> <p>Analysis of two epidemiologically complete databases of individuals admitted for mental illness. 3170 individuals admitted to the North Wales Asylum between 1875–1924 and tracked over 18,486 patient years and 394 North West Wales first admissions for schizophrenia and related psychoses between 1994 and 2006 and tracked after treatment.</p> <p>Results</p> <p>The prevalence of Type 2 diabetes among patients with psychoses at time of first admission in both historical and contemporary samples was 0%. The incidence of diabetes remained 0% in the historical sample throughout 15 years of follow-up but rose in the contemporary sample after 3, 5 and 6 years of treatment with an incidence rate double the expected population rate so that the 15 year prevalence is likely to be over 8%.</p> <p>Conclusion</p> <p>No association was found between diabetes and serious mental illness, but there may be an association between diabetes and treatment.</p>http://www.biomedcentral.com/1471-244X/8/67
spellingShingle Roberts Tony
Williams Dawn
Wong Winnie
Harris Margaret
Khan Afshan
Le Noury Joanna
Tranter Richard
Healy David
The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 compared
BMC Psychiatry
title The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 compared
title_full The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 compared
title_fullStr The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 compared
title_full_unstemmed The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 compared
title_short The incidence and prevalence of diabetes in patients with serious mental illness in North West Wales: Two cohorts, 1875–1924 & 1994–2006 compared
title_sort incidence and prevalence of diabetes in patients with serious mental illness in north west wales two cohorts 1875 1924 1994 2006 compared
url http://www.biomedcentral.com/1471-244X/8/67
work_keys_str_mv AT robertstony theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT williamsdawn theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT wongwinnie theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT harrismargaret theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT khanafshan theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT lenouryjoanna theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT tranterrichard theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT healydavid theincidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT robertstony incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT williamsdawn incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT wongwinnie incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT harrismargaret incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT khanafshan incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT lenouryjoanna incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT tranterrichard incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared
AT healydavid incidenceandprevalenceofdiabetesinpatientswithseriousmentalillnessinnorthwestwalestwocohorts1875192419942006compared