A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West Bengal
Background: Prolactin has multiple biological functions and hyperprolactinaemia is a common condition in clinical practice in both females and males. It has many etiologies and may present with variable symptoms to health care workers. Aims and Objectives: To study the various etiologies and clin...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2021-09-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/37656 |
| _version_ | 1818611726165213184 |
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| author | Debajyoti Tapadar Debjani Sengupta |
| author_facet | Debajyoti Tapadar Debjani Sengupta |
| author_sort | Debajyoti Tapadar |
| collection | DOAJ |
| description | Background: Prolactin has multiple biological functions and hyperprolactinaemia is a common condition in clinical practice in both females and males. It has many etiologies and may present with variable symptoms to health care workers.
Aims and Objectives: To study the various etiologies and clinical presentation of patients presenting with hyperprolactinaemia in a tertiary care medical college and hospital in West Bengal to aid in quick decision management.
Materials and Methods: The current study was a cross-sectional study with follow up conducted over a period of one year in the Department of Gynecology and Obstetrics, Jagannath Gupta Institute of Medical College and Hospital. Following sample size calculation, a total of 1824 women were enrolled for the study of which 53 were found to have raised prolactin level (after following proper inclusion and exclusion criteria) They were subsequently further examined and followed up.
Results: Majority of the subjects studied belonged to 20-29 age group (49.05%) followed by 30-39 years age group (35.85%). The most common cause of hyperprolactinaemia in our study were idiopathic (24.53%) followed by drugs (22.64%) and pituitary adenoma. Most of the patients with hyperprolactinaemia, presented with complain of infertility (56.6%), menstrual abnormality (50.94%) and galactorrhoea (18.87%) in our study. Therapeutic drugs used for various reasons were one of the main cause of hyperprolactinaemia (22.64%) and mainly due to use of proton pump inhibitor with prokinetics use.
Conclusion: Hyperprolactinaemia is very much common in patients with infertility, menstrual abnormality or galactorrhoea and mostly are due to idiopathic or drug induced causes. With early initiation of treatment most of the causes and effects can be cured. |
| first_indexed | 2024-12-16T15:34:54Z |
| format | Article |
| id | doaj.art-c130aa332b604d9480f0f942e00f7982 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-12-16T15:34:54Z |
| publishDate | 2021-09-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-c130aa332b604d9480f0f942e00f79822022-12-21T22:26:13ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762021-09-01129120125https://doi.org/10.3126/ajms.v12i9.37656A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West BengalDebajyoti Tapadar 0https://orcid.org/0000-0003-1983-9343Debjani Sengupta 1https://orcid.org/0000-0002-2026-2660Professor and Head, Department of Gynaecology and Obstetrics, Jagannath Gupta Institute of Medical Sciences and Hospital, Budge Budge, Kolkata, West Bengal, India Assistant Professor, Department of Community Medicine, Calcutta National Medical College Kolkata, West Bengal. India Background: Prolactin has multiple biological functions and hyperprolactinaemia is a common condition in clinical practice in both females and males. It has many etiologies and may present with variable symptoms to health care workers. Aims and Objectives: To study the various etiologies and clinical presentation of patients presenting with hyperprolactinaemia in a tertiary care medical college and hospital in West Bengal to aid in quick decision management. Materials and Methods: The current study was a cross-sectional study with follow up conducted over a period of one year in the Department of Gynecology and Obstetrics, Jagannath Gupta Institute of Medical College and Hospital. Following sample size calculation, a total of 1824 women were enrolled for the study of which 53 were found to have raised prolactin level (after following proper inclusion and exclusion criteria) They were subsequently further examined and followed up. Results: Majority of the subjects studied belonged to 20-29 age group (49.05%) followed by 30-39 years age group (35.85%). The most common cause of hyperprolactinaemia in our study were idiopathic (24.53%) followed by drugs (22.64%) and pituitary adenoma. Most of the patients with hyperprolactinaemia, presented with complain of infertility (56.6%), menstrual abnormality (50.94%) and galactorrhoea (18.87%) in our study. Therapeutic drugs used for various reasons were one of the main cause of hyperprolactinaemia (22.64%) and mainly due to use of proton pump inhibitor with prokinetics use. Conclusion: Hyperprolactinaemia is very much common in patients with infertility, menstrual abnormality or galactorrhoea and mostly are due to idiopathic or drug induced causes. With early initiation of treatment most of the causes and effects can be cured.https://www.nepjol.info/index.php/AJMS/article/view/37656hyperprolactinaemiaidiopathic hyperprolactinaemiadrug induced hyperprolactinaemiainfertility |
| spellingShingle | Debajyoti Tapadar Debjani Sengupta A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West Bengal Asian Journal of Medical Sciences hyperprolactinaemia idiopathic hyperprolactinaemia drug induced hyperprolactinaemia infertility |
| title | A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West Bengal |
| title_full | A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West Bengal |
| title_fullStr | A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West Bengal |
| title_full_unstemmed | A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West Bengal |
| title_short | A study on Hyperprolactinaemia and associated factors among women attending Gynecology outpatient department at a tertiary teaching hospital in West Bengal |
| title_sort | study on hyperprolactinaemia and associated factors among women attending gynecology outpatient department at a tertiary teaching hospital in west bengal |
| topic | hyperprolactinaemia idiopathic hyperprolactinaemia drug induced hyperprolactinaemia infertility |
| url | https://www.nepjol.info/index.php/AJMS/article/view/37656 |
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