A human ESC line for efficient CRISPR editing of pluripotent stem cells
Human pluripotent stem cells (hPSC) can be directed to differentiate in vitro into insulin-prorducing beta cells (SC-β). Although these cells accurately respond to glucose and can reverse diabetes in preclinical models improvments in the final cell products are desirable. For example, safety, contro...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-12-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506121004384 |