The Role of T Cell Immunity in Monoclonal Gammopathy and Multiple Myeloma: From Immunopathogenesis to Novel Therapeutic Approaches

The Role of T Cell Immunity in Monoclonal Gammopathy and Multiple Myeloma: From Immunopathogenesis to Novel Therapeutic Approaches

Multiple Myeloma (MM) is a malignant growth of clonal plasma cells, typically arising from asymptomatic precursor conditions, namely monoclonal gammopathy of undetermined significance (MGUS) and smoldering MM (SMM). Profound immunological dysfunctions and cytokine deregulation are known to character...

Full description

Bibliographic Details
Main Authors: Ivana Lagreca, Giovanni Riva, Vincenzo Nasillo, Patrizia Barozzi, Ilaria Castelli, Sabrina Basso, Francesca Bettelli, Davide Giusti, Angela Cuoghi, Paola Bresciani, Andrea Messerotti, Andrea Gilioli, Valeria Pioli, Corrado Colasante, Daniela Vallerini, Ambra Paolini, Monica Maccaferri, Francesca Donatelli, Fabio Forghieri, Monica Morselli, Elisabetta Colaci, Giovanna Leonardi, Roberto Marasca, Leonardo Potenza, Rossella Manfredini, Enrico Tagliafico, Tommaso Trenti, Patrizia Comoli, Mario Luppi
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
MGUS
multiple myeloma
plasma cells
T cell immunity
tumor microenvironment
immunotherapy
Online Access:https://www.mdpi.com/1422-0067/23/9/5242

Internet

https://www.mdpi.com/1422-0067/23/9/5242

Similar Items