Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy.

Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy.

Absence epilepsy (AE) is a common type of genetic generalized epilepsy (GGE), particularly in children. AE and GGE are complex genetic diseases with few causal variants identified to date. Gria4 deficient mice provide a model of AE, one for which the common laboratory inbred strain C3H/HeJ (HeJ) har...

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Bibliographic Details
Main Authors: Wayne N Frankel, Connie L Mahaffey, Tracy C McGarr, Barbara J Beyer, Verity A Letts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4091709?pdf=render

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