Prescription medication use of United States military service members by therapeutic classification

Background: This cross-sectional study investigated the prevalence of, and factors associated with, filled prescription medications (FPMs) among United States (US) service members (SMs).Methods: A stratified random sample of active duty SMs from the Air Force, Army, Marine Corps, and Navy was obtain...

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Main Authors: Joseph J. Knapik, Daniel W. Trone, Ryan A. Steelman, Emily K. Farina, Harris R. Lieberman
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.972031/full
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author Joseph J. Knapik
Daniel W. Trone
Ryan A. Steelman
Emily K. Farina
Harris R. Lieberman
author_facet Joseph J. Knapik
Daniel W. Trone
Ryan A. Steelman
Emily K. Farina
Harris R. Lieberman
author_sort Joseph J. Knapik
collection DOAJ
description Background: This cross-sectional study investigated the prevalence of, and factors associated with, filled prescription medications (FPMs) among United States (US) service members (SMs).Methods: A stratified random sample of active duty SMs from the Air Force, Army, Marine Corps, and Navy was obtained from military workforce records. Participants (n = 26,680) completed a questionnaire on demographics, physical characteristics, and lifestyle factors and approved access to their FPM for the previous 6 months. FPMs were obtained from the military Pharmacy Data Transaction Service that included all prescription medications dispensed at military medical treatment facilities, abroad, at retail pharmacies in the US, and/or through mail-order programs.Results: About two-thirds (65%) of SMs had ≥1 FPM in the 6 months surveillance period. Central nervous system (CNS) agents had the highest prevalence (41%), followed by anti-infective agents (20%), eye/ear/nose/throat preparations (20%), gastrointestinal drugs (18%), autonomic drugs (17%), skin and mucous membrane agents (13%), antihistamine drugs (12%), respiratory tract agents (12%) and cardiovascular drugs (9%). Among CNS agents, overall prevalence of dispensed non-steroidal anti-inflammatory drug (NSAIDs) was 30%. The odds of any FPM was independently associated with female gender, older age, higher body mass index, former tobacco use (smoking and smokeless tobacco), lower alcohol consumption, and was highest among Army, lowest among Marine Corps personnel.Conclusion: In this sample of SMs, dispensing of prescription medication was high, especially NSAIDs, but dispensing of cardiovascular drugs was much lower compared to the general US population, likely because of the younger age and higher level of physical activity of SMs.
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spelling doaj.art-c136dc443ed9473aa29009fa8b3631fb2022-12-22T03:21:46ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122022-09-011310.3389/fphar.2022.972031972031Prescription medication use of United States military service members by therapeutic classificationJoseph J. Knapik0Daniel W. Trone1Ryan A. Steelman2Emily K. Farina3Harris R. Lieberman4Military Nutrition Division, United States Army Research Institute of Environmental Medicine, Natick, MA, United StatesNaval Health Research Center, San Diego, CA, United StatesUnited States Army Public Health Center, Aberdeen Proving Ground, MD, United StatesMilitary Nutrition Division, United States Army Research Institute of Environmental Medicine, Natick, MA, United StatesMilitary Nutrition Division, United States Army Research Institute of Environmental Medicine, Natick, MA, United StatesBackground: This cross-sectional study investigated the prevalence of, and factors associated with, filled prescription medications (FPMs) among United States (US) service members (SMs).Methods: A stratified random sample of active duty SMs from the Air Force, Army, Marine Corps, and Navy was obtained from military workforce records. Participants (n = 26,680) completed a questionnaire on demographics, physical characteristics, and lifestyle factors and approved access to their FPM for the previous 6 months. FPMs were obtained from the military Pharmacy Data Transaction Service that included all prescription medications dispensed at military medical treatment facilities, abroad, at retail pharmacies in the US, and/or through mail-order programs.Results: About two-thirds (65%) of SMs had ≥1 FPM in the 6 months surveillance period. Central nervous system (CNS) agents had the highest prevalence (41%), followed by anti-infective agents (20%), eye/ear/nose/throat preparations (20%), gastrointestinal drugs (18%), autonomic drugs (17%), skin and mucous membrane agents (13%), antihistamine drugs (12%), respiratory tract agents (12%) and cardiovascular drugs (9%). Among CNS agents, overall prevalence of dispensed non-steroidal anti-inflammatory drug (NSAIDs) was 30%. The odds of any FPM was independently associated with female gender, older age, higher body mass index, former tobacco use (smoking and smokeless tobacco), lower alcohol consumption, and was highest among Army, lowest among Marine Corps personnel.Conclusion: In this sample of SMs, dispensing of prescription medication was high, especially NSAIDs, but dispensing of cardiovascular drugs was much lower compared to the general US population, likely because of the younger age and higher level of physical activity of SMs.https://www.frontiersin.org/articles/10.3389/fphar.2022.972031/fullcentral nervous system agentsnon-steroidal anti-inflammatory agentsantiinfective agentsanalgesics and antipyreticscentrally acting skeletal muscle relaxantsantidepressants
spellingShingle Joseph J. Knapik
Daniel W. Trone
Ryan A. Steelman
Emily K. Farina
Harris R. Lieberman
Prescription medication use of United States military service members by therapeutic classification
Frontiers in Pharmacology
central nervous system agents
non-steroidal anti-inflammatory agents
antiinfective agents
analgesics and antipyretics
centrally acting skeletal muscle relaxants
antidepressants
title Prescription medication use of United States military service members by therapeutic classification
title_full Prescription medication use of United States military service members by therapeutic classification
title_fullStr Prescription medication use of United States military service members by therapeutic classification
title_full_unstemmed Prescription medication use of United States military service members by therapeutic classification
title_short Prescription medication use of United States military service members by therapeutic classification
title_sort prescription medication use of united states military service members by therapeutic classification
topic central nervous system agents
non-steroidal anti-inflammatory agents
antiinfective agents
analgesics and antipyretics
centrally acting skeletal muscle relaxants
antidepressants
url https://www.frontiersin.org/articles/10.3389/fphar.2022.972031/full
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