Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and Bioactivity
<b>Background</b>: The genus <i>Stachys</i> L. (Lamiaceae) includes about 300 species as annual or perennial herbs or small shrubs, spread in temperate regions of Mediterranean, Asia, America and southern Africa. Several species of this genus are extensively used in various t...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-09-01
|
| Series: | Medicines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2305-6320/7/10/63 |
| _version_ | 1797416609660272640 |
|---|---|
| author | Ekaterina-Michaela Tomou Christina Barda Helen Skaltsa |
| author_facet | Ekaterina-Michaela Tomou Christina Barda Helen Skaltsa |
| author_sort | Ekaterina-Michaela Tomou |
| collection | DOAJ |
| description | <b>Background</b>: The genus <i>Stachys</i> L. (Lamiaceae) includes about 300 species as annual or perennial herbs or small shrubs, spread in temperate regions of Mediterranean, Asia, America and southern Africa. Several species of this genus are extensively used in various traditional medicines. They are consumed as herbal preparations for the treatment of stress, skin inflammations, gastrointestinal disorders, asthma and genital tumors. Previous studies have investigated the chemical constituents and the biological activities of these species. Thus, the present review compiles literature data on ethnomedicine, phytochemistry, pharmacological activities, clinical studies and the toxicity of genus <i>Stachys</i>. <b>Methods</b>: Comprehensive research of previously published literature was performed for studies on the traditional uses, bioactive compounds and pharmacological properties of the genus <i>Stachys</i>, using databases with different key search words. <b>Results</b>: This survey documented 60 <i>Stachys</i> species and 10 subspecies for their phytochemical profiles, including 254 chemical compounds and reported 19 species and 4 subspecies for their pharmacological properties. Furthermore, 25 species and 6 subspecies were found for their traditional uses. <b>Conclusions</b>: The present review highlights that <i>Stachys</i> spp. consist an important source of bioactive phytochemicals and exemplifies the uncharted territory of this genus for new research studies. |
| first_indexed | 2024-03-09T06:06:37Z |
| format | Article |
| id | doaj.art-c13792f6ea794fed8be95c55204b55f5 |
| institution | Directory Open Access Journal |
| issn | 2305-6320 |
| language | English |
| last_indexed | 2024-03-09T06:06:37Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicines |
| spelling | doaj.art-c13792f6ea794fed8be95c55204b55f52023-12-03T12:03:40ZengMDPI AGMedicines2305-63202020-09-017106310.3390/medicines7100063Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and BioactivityEkaterina-Michaela Tomou0Christina Barda1Helen Skaltsa2Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, GreeceDepartment of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, GreeceDepartment of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece<b>Background</b>: The genus <i>Stachys</i> L. (Lamiaceae) includes about 300 species as annual or perennial herbs or small shrubs, spread in temperate regions of Mediterranean, Asia, America and southern Africa. Several species of this genus are extensively used in various traditional medicines. They are consumed as herbal preparations for the treatment of stress, skin inflammations, gastrointestinal disorders, asthma and genital tumors. Previous studies have investigated the chemical constituents and the biological activities of these species. Thus, the present review compiles literature data on ethnomedicine, phytochemistry, pharmacological activities, clinical studies and the toxicity of genus <i>Stachys</i>. <b>Methods</b>: Comprehensive research of previously published literature was performed for studies on the traditional uses, bioactive compounds and pharmacological properties of the genus <i>Stachys</i>, using databases with different key search words. <b>Results</b>: This survey documented 60 <i>Stachys</i> species and 10 subspecies for their phytochemical profiles, including 254 chemical compounds and reported 19 species and 4 subspecies for their pharmacological properties. Furthermore, 25 species and 6 subspecies were found for their traditional uses. <b>Conclusions</b>: The present review highlights that <i>Stachys</i> spp. consist an important source of bioactive phytochemicals and exemplifies the uncharted territory of this genus for new research studies.https://www.mdpi.com/2305-6320/7/10/63<i>Stachys</i> L.traditional usespharmacological activitiesphytochemicalsbioactive compounds |
| spellingShingle | Ekaterina-Michaela Tomou Christina Barda Helen Skaltsa Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and Bioactivity Medicines <i>Stachys</i> L. traditional uses pharmacological activities phytochemicals bioactive compounds |
| title | Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and Bioactivity |
| title_full | Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and Bioactivity |
| title_fullStr | Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and Bioactivity |
| title_full_unstemmed | Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and Bioactivity |
| title_short | Genus <i>Stachys</i>: A Review of Traditional Uses, Phytochemistry and Bioactivity |
| title_sort | genus i stachys i a review of traditional uses phytochemistry and bioactivity |
| topic | <i>Stachys</i> L. traditional uses pharmacological activities phytochemicals bioactive compounds |
| url | https://www.mdpi.com/2305-6320/7/10/63 |
| work_keys_str_mv | AT ekaterinamichaelatomou genusistachysiareviewoftraditionalusesphytochemistryandbioactivity AT christinabarda genusistachysiareviewoftraditionalusesphytochemistryandbioactivity AT helenskaltsa genusistachysiareviewoftraditionalusesphytochemistryandbioactivity |