Systemic Protein Delivery via Inhalable Liposomes: Formulation and Pharmacokinetics

Systemic Protein Delivery via Inhalable Liposomes: Formulation and Pharmacokinetics

The enormous and thin alveolar epithelium is an attractive site for systemic protein delivery. Considering the excellent biocompatibility of phospholipids with endogenous pulmonary surfactant, we engineered dimyristoylphosphatidylcholine (DMPC)-based liposomes for pulmonary administration, using Cy5...

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Bibliographic Details
Main Authors: Pranav Ponkshe, Yingzhe Wang, Chalet Tan
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
inhalable liposome
DMPC
systemic protein delivery
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/15/7/1951

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