Neuropilin-1 Knockout and Rescue Confirms Its Role to Promote Metastasis in MDA-MB-231 Breast Cancer Cells

Neuropilin-1 Knockout and Rescue Confirms Its Role to Promote Metastasis in MDA-MB-231 Breast Cancer Cells

Breast cancer (BC) metastasis remains a leading cause of female mortality. Neuropilin-1 (NRP-1) is a glycoprotein receptor that plays ligand-dependent roles in BC. Clinical studies indicate its correlation with metastatic disease; however, its functional role in BC metastasis remains uncertain. CRIS...

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Bibliographic Details
Main Authors: Noura Al-Zeheimi, Yan Gao, Peter A. Greer, Sirin A. Adham
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
neuropilin-1
knockout
breast cancer
metastasis
CRISPR
transcriptome
Online Access:https://www.mdpi.com/1422-0067/24/9/7792

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