Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection
Despite the availability of a safe and effective vaccine, measles remains the leading cause of child death among vaccine-preventable diseases. In this work, authors utilised a cynomolgus macaque model of infection, and a mesh nebuliser administration approach, to show efficacy of their aerosolized l...
Main Authors: | Olivier Reynard, Claudia Gonzalez, Claire Dumont, Mathieu Iampietro, Marion Ferren, Sandrine Le Guellec, Lajoie Laurie, Cyrille Mathieu, Gabrielle Carpentier, Georges Roseau, Francesca T. Bovier, Yun Zhu, Deborah Le Pennec, Jérome Montharu, Amin Addetia, Alexander L. Greninger, Christopher A. Alabi, Elise Brisebard, Anne Moscona, Laurent Vecellio, Matteo Porotto, Branka Horvat |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33832-6 |
Similar Items
-
Early Permissiveness of Central Nervous System Cells to Measles Virus Infection Is Determined by Hyperfusogenicity and Interferon Pressure
by: Marion Ferren, et al.
Published: (2023-01-01) -
Molecular Features of the Measles Virus Viral Fusion Complex That Favor Infection and Spread in the Brain
by: Cyrille Mathieu, et al.
Published: (2021-06-01) -
Viral Entry Properties Required for Fitness in Humans Are Lost through Rapid Genomic Change during Viral Isolation
by: Sho Iketani, et al.
Published: (2018-09-01) -
Inhalation d'aérosols liquides ou solides chez les Primates Non Humains
by: Jérôme Montharu, et al.
Published: (2015-03-01) -
Measles Fusion Machinery Is Dysregulated in Neuropathogenic Variants
by: Eric M. Jurgens, et al.
Published: (2015-02-01)