In-house ammonia induced lung impairment and oxidative stress of ducks
ABSTRACT: Ammonia (NH3) is a toxic gas that in intensive poultry houses, damages the poultry health and induces various diseases. This study investigated the effects of NH3 exposure (0, 15, 30, and 45 ppm) on growth performance, serum biochemical indexes, antioxidative indicators, tracheal and lung...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Poultry Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579124002013 |
| _version_ | 1797249235652968448 |
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| author | Bo Liu Yongjie Yang Yang Fu Yue Zhao Wenjing Chen Shi Wei Xin Zuo Yongwen Zhu Hui Ye Minhong Zhang Peng Zhang Lin Yang Wence Wang Jie Pan |
| author_facet | Bo Liu Yongjie Yang Yang Fu Yue Zhao Wenjing Chen Shi Wei Xin Zuo Yongwen Zhu Hui Ye Minhong Zhang Peng Zhang Lin Yang Wence Wang Jie Pan |
| author_sort | Bo Liu |
| collection | DOAJ |
| description | ABSTRACT: Ammonia (NH3) is a toxic gas that in intensive poultry houses, damages the poultry health and induces various diseases. This study investigated the effects of NH3 exposure (0, 15, 30, and 45 ppm) on growth performance, serum biochemical indexes, antioxidative indicators, tracheal and lung impairments in Pekin ducks. A total of 288 one-day-old Pekin male ducks were randomly allocated to 4 groups with 6 replicates and slaughtered after the 21-d test period. Our results showed that 45 ppm NH3 significantly reduced the average daily feed intake (ADFI) of Pekin ducks. Ammonia exposure significantly reduced liver, lung, kidney, and heart indexes, and lowered the relative weight of the ileum. With the increasing of in-house NH3, serum NH3 and uric acid (UA) concentrations of ducks were significantly increased, as well as liver malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPX-Px) contents. High NH3 also induced trachea and lung injury, thereby increasing levels of tumor necrosis factor-α (TNF-α) and interleukin-4 (IL-4) in the lung, and decreasing the mRNA expressions of zonula occludens 1 (ZO-1) and claudin 3 (CLDN3) in the lung. In conclusion, in-house NH3 decrease the growth performance in ducks, induce trachea and lung injuries and meanwhile increase the compensatory antioxidant activity for host protection. |
| first_indexed | 2024-04-24T20:27:16Z |
| format | Article |
| id | doaj.art-c13c612a7dc4426487d6d8c13e3a0681 |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-04-24T20:27:16Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-c13c612a7dc4426487d6d8c13e3a06812024-03-22T05:38:25ZengElsevierPoultry Science0032-57912024-05-011035103622In-house ammonia induced lung impairment and oxidative stress of ducksBo Liu0Yongjie Yang1Yang Fu2Yue Zhao3Wenjing Chen4Shi Wei5Xin Zuo6Yongwen Zhu7Hui Ye8Minhong Zhang9Peng Zhang10Lin Yang11Wence Wang12Jie Pan13State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, China; Changsha Sanwang Feed Co. Ltd, Changsha, ChinaKey Laboratory of Animal Nutrition and Healthy Breeding, Ministry of Agriculture, Wen's Foodstuff Group Co. Ltd, Yunfu, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, ChinaKey Laboratory of Animal Nutrition and Healthy Breeding, Ministry of Agriculture, Wen's Foodstuff Group Co. Ltd, Yunfu, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, ChinaState Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Pekin, ChinaChimelong Group Co., Guangzhou 511430, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, ChinaState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University Guangzhou, China; Corresponding author:Hunan Shihua Biotech Co. Ltd., Changsha, ChinaABSTRACT: Ammonia (NH3) is a toxic gas that in intensive poultry houses, damages the poultry health and induces various diseases. This study investigated the effects of NH3 exposure (0, 15, 30, and 45 ppm) on growth performance, serum biochemical indexes, antioxidative indicators, tracheal and lung impairments in Pekin ducks. A total of 288 one-day-old Pekin male ducks were randomly allocated to 4 groups with 6 replicates and slaughtered after the 21-d test period. Our results showed that 45 ppm NH3 significantly reduced the average daily feed intake (ADFI) of Pekin ducks. Ammonia exposure significantly reduced liver, lung, kidney, and heart indexes, and lowered the relative weight of the ileum. With the increasing of in-house NH3, serum NH3 and uric acid (UA) concentrations of ducks were significantly increased, as well as liver malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPX-Px) contents. High NH3 also induced trachea and lung injury, thereby increasing levels of tumor necrosis factor-α (TNF-α) and interleukin-4 (IL-4) in the lung, and decreasing the mRNA expressions of zonula occludens 1 (ZO-1) and claudin 3 (CLDN3) in the lung. In conclusion, in-house NH3 decrease the growth performance in ducks, induce trachea and lung injuries and meanwhile increase the compensatory antioxidant activity for host protection.http://www.sciencedirect.com/science/article/pii/S0032579124002013ammoniaduckgrowth performancetrachealung |
| spellingShingle | Bo Liu Yongjie Yang Yang Fu Yue Zhao Wenjing Chen Shi Wei Xin Zuo Yongwen Zhu Hui Ye Minhong Zhang Peng Zhang Lin Yang Wence Wang Jie Pan In-house ammonia induced lung impairment and oxidative stress of ducks Poultry Science ammonia duck growth performance trachea lung |
| title | In-house ammonia induced lung impairment and oxidative stress of ducks |
| title_full | In-house ammonia induced lung impairment and oxidative stress of ducks |
| title_fullStr | In-house ammonia induced lung impairment and oxidative stress of ducks |
| title_full_unstemmed | In-house ammonia induced lung impairment and oxidative stress of ducks |
| title_short | In-house ammonia induced lung impairment and oxidative stress of ducks |
| title_sort | in house ammonia induced lung impairment and oxidative stress of ducks |
| topic | ammonia duck growth performance trachea lung |
| url | http://www.sciencedirect.com/science/article/pii/S0032579124002013 |
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