Transcriptome modulation by hydrocortisone in severe burn shock: ancillary analysis of a prospective randomized trial

Transcriptome modulation by hydrocortisone in severe burn shock: ancillary analysis of a prospective randomized trial

Abstract Background Despite shortening vasopressor use in shock, hydrocortisone administration remains controversial, with potential harm to the immune system. Few studies have assessed the impact of hydrocortisone on the transcriptional response in shock, and we are lacking data on burn shock. Our...

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Bibliographic Details
Main Authors: Jonathan Plassais, Fabienne Venet, Marie-Angélique Cazalis, Diane Le Quang, Alexandre Pachot, Guillaume Monneret, Sylvie Tissot, Julien Textoris
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Critical Care
Subjects:
Shock
Burns
Hydrocortisone
Transcriptome modulation
Immunosuppression
Host response
Online Access:http://link.springer.com/article/10.1186/s13054-017-1743-9

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