Extracellular vesicle DNA from human melanoma tissues contains cancer-specific mutations

Extracellular vesicle DNA from human melanoma tissues contains cancer-specific mutations

Liquid biopsies are promising tools for early diagnosis and residual disease monitoring in patients with cancer, and circulating tumor DNA isolated from plasma has been extensively studied as it has been shown to contain tumor-specific mutations. Extracellular vesicles (EVs) present in tumor tissues...

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Bibliographic Details
Main Authors: Rossella Crescitelli, Stefan Filges, Nasibeh Karimi, Ornella Urzì, Tamara Alonso-Agudo, Anders Ståhlberg, Jan Lötvall, Cecilia Lässer, Roger Olofsson Bagge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
tumor-derived extracellular vesicles
melanoma
DNA
ultrasensitive DNA sequencing
SiMSen-Seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1028854/full

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