Global identification of genes related to nutrient deficiency in intervertebral disc cells in an experimental nutrient deprivation model.

Global identification of genes related to nutrient deficiency in intervertebral disc cells in an experimental nutrient deprivation model.

BACKGROUND: Intervertebral disc degeneration is a significant cause of degenerative spinal diseases. Nucleus pulposus (NP) cells reportedly fail to survive in large degenerated discs with limited nutrient availability. Therefore, understanding the regulatory mechanism of the molecular response of NP...

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Bibliographic Details
Main Authors:	Hideki Sudo, Katsuhisa Yamada, Koji Iwasaki, Hideaki Higashi, Manabu Ito, Akio Minami, Norimasa Iwasaki
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3592817?pdf=render

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